PYD and CARD domain containing

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:35.50 動脈:357.10 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:117.10 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:77.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:50.70    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_172322
Gene ID 282817
Unigene ID Rn.7817
Probe set ID -
Ensembl ID ENSRNOG00000019675

オーソログ対応遺伝子

ヒト[3]  NM_013258, NM_145182, NM_152901
マウス[2]  NM_023258, NM_145182, NM_152901

染色体

1q36  [187,276,089  -  187,277,122]

遺伝子ファミリー (Interpro ID)

IPR001315  Caspase Recruitment
IPR011029  DEATH-like
IPR004020  Pyrin

Link to Pubmed  (Pubmed ID)

11139337
12464617
18367607
19302047
19401709
19416975
20303873

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0002218  activation of innate immune response
GO:0071347  cellular response to interleukin-1
GO:0071222  cellular response to lipopolysaccharide
GO:0071356  cellular response to tumor necrosis factor
GO:0050829  defense response to Gram-negative bacterium
GO:0051607  defense response to virus
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006917  induction of apoptosis
GO:0006954  inflammatory response
GO:0032611  interleukin-1 beta production
GO:0001773  myeloid dendritic cell activation
GO:0002277  myeloid dendritic cell activation during immune response
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032688  negative regulation of interferon-beta production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0030838  positive regulation of actin filament polymerization
GO:0042104  positive regulation of activated T cell proliferation
GO:0002821  positive regulation of adaptive immune response
GO:0002588  positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0090197  positive regulation of chemokine secretion
GO:0002230  positive regulation of defense response to virus by host
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0032729  positive regulation of interferon-gamma production
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0050766  positive regulation of phagocytosis
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0050870  positive regulation of T cell activation
GO:0051091  positive regulation of transcription factor activity
GO:0032760  positive regulation of tumor necrosis factor production
GO:0006508  proteolysis
GO:0042981  regulation of apoptosis
GO:0043281  regulation of caspase activity
GO:0031647  regulation of protein stability
GO:0032314  regulation of Rac GTPase activity
GO:0010803  regulation of tumor necrosis factor-mediated signaling pathway
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0008385  IkappaB kinase complex
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0032090  Pyrin domain binding