paired box 2

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:38 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001106361
Gene ID 293992
Unigene ID Rn.137112
Probe set ID -
Ensembl ID ENSRNOG00000014253

オーソログ対応遺伝子

ヒト[10]  NM_000278, NM_003987, NM_003988, NM_003989, NM_003990
マウス[1]  NM_011037, NM_003987, NM_003988, NM_003989, NM_003990

染色体

1q54  [249,804,055  -  249,895,306]

遺伝子ファミリー (Interpro ID)

IPR009057  Homeodomain-like
IPR001523  Paired box protein, N-terminal
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

7937920
11262416
12057921
12444203
15149326
15569307
18489730
18639218
20486844
21778682
23107969
23503776

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007568  aging
GO:0048854  brain morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0043010  camera-type eye development
GO:0001709  cell fate determination
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071333  cellular response to glucose stimulus
GO:0070301  cellular response to hydrogen peroxide
GO:0071260  cellular response to mechanical stimulus
GO:0071300  cellular response to retinoic acid
GO:0090102  cochlea development
GO:0090103  cochlea morphogenesis
GO:0010001  glial cell differentiation
GO:0042472  inner ear morphogenesis
GO:0001822  kidney development
GO:0060231  mesenchymal to epithelial transition
GO:0003337  mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0007501  mesodermal cell fate specification
GO:0001823  mesonephros development
GO:0001656  metanephros development
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0045918  negative regulation of cytolysis
GO:0043069  negative regulation of programmed cell death
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001843  neural tube closure
GO:0002072  optic cup morphogenesis involved in camera-type eye development
GO:0021554  optic nerve development
GO:0021631  optic nerve morphogenesis
GO:0021633  optic nerve structural organization
GO:0048513  organ development
GO:0055114  oxidation reduction
GO:0031016  pancreas development
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0048793  pronephros development
GO:0043491  protein kinase B signaling cascade
GO:0042981  regulation of apoptosis
GO:0043067  regulation of programmed cell death
GO:0031667  response to nutrient levels
GO:0003406  retinal pigment epithelium development
GO:0048863  stem cell differentiation
GO:0006351  transcription, DNA-dependent
GO:0001657  ureteric bud development
GO:0001655  urogenital system development
GO:0021650  vestibulocochlear nerve formation

Cellular Component

GO:0034451  centriolar satellite
GO:0005764  lysosome
GO:0005815  microtubule organizing center
GO:0005634  nucleus
GO:0043234  protein complex
GO:0032993  protein-DNA complex

Molecular Function

GO:0070742  C2H2 zinc finger domain binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0043565  sequence-specific DNA binding
GO:0016175  superoxide-generating NADPH oxidase activity
GO:0003700  transcription factor activity