mitogen-activated protein kinase kinase kinase 11

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:35.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:36.90 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:122.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:238.90 前立腺:113.90 卵巣:- 精巣:82.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:101.30    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001013150
Gene ID 309168
Unigene ID Rn.28235
Probe set ID -
Ensembl ID ENSRNOG00000020773

オーソログ対応遺伝子

ヒト[1]  NM_002419
マウス[1]  NM_022012

染色体

1q43  [208,312,955  -  208,325,686]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8910292
11416147
11438570
12477932
14575811
14690535
15069087
15489334
15680699
15797868
16154687
17064355
17161586
17306896
17348686
17711861
18307989
19368836
19546888
20626350
21726169
22123824

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007256  activation of JNKK activity
GO:0007257  activation of JUN kinase activity
GO:0000187  activation of MAPK activity
GO:0008219  cell death
GO:0008283  cell proliferation
GO:0000080  G1 phase of mitotic cell cycle
GO:0007254  JNK cascade
GO:0007017  microtubule-based process
GO:0043065  positive regulation of apoptosis
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0043525  positive regulation of neuron apoptosis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005874  microtubule

Molecular Function

GO:0005524  ATP binding
GO:0042802  identical protein binding
GO:0004706  JUN kinase kinase kinase activity
GO:0004709  MAP kinase kinase kinase activity
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004674  protein serine/threonine kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0048365  Rac GTPase binding