secreted frizzled-related protein 2

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:35.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:294.40 骨:39 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:38 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:101.30    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001100700
Gene ID 310552
Unigene ID Rn.102416
Probe set ID -
Ensembl ID ENSRNOG00000009465

オーソログ対応遺伝子

ヒト[1]  NM_003013
マウス[1]  NM_009144

染色体

2q34  [175,479,320  -  175,486,864]

遺伝子ファミリー (Interpro ID)

IPR020067  Frizzled-like domain
IPR001134  Netrin domain
IPR018933  Netrin module, non-TIMP type
IPR008993  TIMP-like, OB-fold

Link to Pubmed  (Pubmed ID)

12477932
14561758
16077992
17251350
17341692
19109969
21078975
22290867
23085770

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0006915  apoptosis
GO:0060349  bone morphogenesis
GO:0007420  brain development
GO:0003214  cardiac left ventricle morphogenesis
GO:0051216  cartilage development
GO:0008219  cell death
GO:0031668  cellular response to extracellular stimulus
GO:0071481  cellular response to X-ray
GO:0002063  chondrocyte development
GO:0030199  collagen fibril organization
GO:0060028  convergent extension involved in axis elongation
GO:0046546  development of primary male sexual characteristics
GO:0048546  digestive tract morphogenesis
GO:0009790  embryonic development
GO:0042733  embryonic digit morphogenesis
GO:0008406  gonad development
GO:0071425  hemopoietic stem cell proliferation
GO:0008584  male gonad development
GO:0030514  negative regulation of BMP signaling pathway
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0043154  negative regulation of caspase activity
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0010629  negative regulation of gene expression
GO:0043508  negative regulation of JUN kinase activity
GO:0042662  negative regulation of mesodermal cell fate specification
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001843  neural tube closure
GO:0021915  neural tube development
GO:0003151  outflow tract morphogenesis
GO:0001569  patterning of blood vessels
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0045766  positive regulation of angiogenesis
GO:0043065  positive regulation of apoptosis
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0010950  positive regulation of endopeptidase activity
GO:0045600  positive regulation of fat cell differentiation
GO:0045669  positive regulation of osteoblast differentiation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042981  regulation of apoptosis
GO:0042127  regulation of cell proliferation
GO:0090175  regulation of establishment of planar polarity
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0042493  response to drug
GO:0007584  response to nutrient
GO:0001756  somitogenesis
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0005886  plasma membrane

Molecular Function

GO:0010577  metalloenzyme activator activity
GO:0003674  molecular_function
GO:0030165  PDZ domain binding
GO:0048018  receptor agonist activity
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding