interleukin-1 receptor-associated kinase 3

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:36.90 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:117.10 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:38 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:113.80 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001108101
Gene ID 314870
Unigene ID Rn.147737
Probe set ID -
Ensembl ID ENSRNOG00000004226

オーソログ対応遺伝子

ヒト[4]  NM_001142523, NM_007199
マウス[1]  NM_028679, NM_007199

染色体

7q22  [59,408,211  -  59,467,896]

遺伝子ファミリー (Interpro ID)

IPR000488  Death
IPR011029  DEATH-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

12477932
18497707

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0019221  cytokine-mediated signaling pathway
GO:0070498  interleukin-1-mediated signaling pathway
GO:0045824  negative regulation of innate immune response
GO:0032695  negative regulation of interleukin-12 production
GO:0032715  negative regulation of interleukin-6 production
GO:0010936  negative regulation of macrophage cytokine production
GO:0043407  negative regulation of MAP kinase activity
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0042177  negative regulation of protein catabolic process
GO:0043242  negative regulation of protein complex disassembly
GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0032720  negative regulation of tumor necrosis factor production
GO:0010933  positive regulation of macrophage tolerance induction
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0043244  regulation of protein complex disassembly
GO:0043330  response to exogenous dsRNA
GO:0070555  response to interleukin-1
GO:0032496  response to lipopolysaccharide
GO:0032494  response to peptidoglycan

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0000287  magnesium ion binding
GO:0003674  molecular_function
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity