lysine (K)-specific demethylase 1

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:95.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:35.50 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:78 胸腺:245.80 骨髄:- 脂肪:147.20 骨:117.10 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:79.60 前立腺:75.90 卵巣:- 精巣:82.30 心臓:77.60 骨格筋:531.50 食道:- 胃:- 腸:- 結腸:289.90     肝臓:39.90        肺:-    膀胱:- 腎臓:255.20 下垂体:59.20 甲状腺:- 副腎:- 膵臓:113.80 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001130098
Gene ID 500569
Unigene ID Rn.203461
Probe set ID -
Ensembl ID ENSRNOG00000022372

オーソログ対応遺伝子

ヒト[4]  NM_001009999, NM_015013
マウス[2]  NM_133872, NM_015013

染色体

5q36  [155,299,289  -  155,344,793]

遺伝子ファミリー (Interpro ID)

IPR006076  FAD dependent oxidoreductase

Link to Pubmed  (Pubmed ID)

20418916
20542065
21124846
22082260
23516587
24111946

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0030851  granulocyte differentiation
GO:0034720  histone H3-K4 demethylation
GO:0033169  histone H3-K9 demethylation
GO:0001701  in utero embryonic development
GO:0055001  muscle cell development
GO:0043066  negative regulation of apoptosis
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0051572  negative regulation of histone H3-K4 methylation
GO:0051573  negative regulation of histone H3-K9 methylation
GO:0032091  negative regulation of protein binding
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0021983  pituitary gland development
GO:0045648  positive regulation of erythrocyte differentiation
GO:0046886  positive regulation of hormone biosynthetic process
GO:0045654  positive regulation of megakaryocyte differentiation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006482  protein amino acid demethylation
GO:0010725  regulation of primitive erythrocyte differentiation
GO:0006357  regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0050681  androgen receptor binding
GO:0003682  chromatin binding
GO:0032451  demethylase activity
GO:0044212  DNA regulatory region binding
GO:0019899  enzyme binding
GO:0050660  FAD binding
GO:0032452  histone demethylase activity
GO:0034648  histone demethylase activity (H3-dimethyl-K4 specific)
GO:0032453  histone demethylase activity (H3-K4 specific)
GO:0032454  histone demethylase activity (H3-K9 specific)
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0043426  MRF binding
GO:0016491  oxidoreductase activity
GO:0002039  p53 binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding