phosphodiesterase 2A, cGMP-stimulated

 詳細情報を見る

同義遺伝子名

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発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:23.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:36.90 脊柱:- 網膜:- 目:71.10 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:8.63 小脳:7.25 脳幹:7.72 脳梁:- 松果体:- 末梢神経:8.81 脊柱:- 網膜:- 目:7.75 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:7.57 胸腺:7.28 骨髄:7.35 脂肪:- 骨:- 皮膚:-
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:119.50 前立腺:- 卵巣:- 精巣:- 心臓:96.90 骨格筋:- 食道:- 胃:- 腸:209.30 結腸:-     肝臓:-        肺:50.70    膀胱:- 腎臓:63.80 下垂体:118.40 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:7.43 骨格筋:7.38 食道:- 胃:- 腸:7.30 結腸:8.13 肝臓:- 肺:- 膀胱:- 腎臓:7.32 下垂体:7.37 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001143847
Gene ID 81743
Unigene ID Rn.100440
Probe set ID U21101_at  [RG_U34A]
Ensembl ID ENSRNOG00000019560

オーソログ対応遺伝子

ヒト[3]  NM_001143839, NM_001146209, NM_002599
マウス[3]  NM_001008548, NM_001143848, NM_001143849

染色体

1q32  [158,921,607  -  159,013,829]

遺伝子ファミリー (Interpro ID)

IPR002073  3'5'-cyclic nucleotide phosphodiesterase
IPR003018  GAF
IPR003607  Metal-dependent phosphohydrolase, HD domain

Link to Pubmed  (Pubmed ID)

1326532
7811274
12107056
12573460
12834273
16651469
17329248
17376027
17561940
18499090
18684888
19003918
19506089
20175220
21724846
23000621

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006198  cAMP catabolic process
GO:0019933  cAMP-mediated signaling
GO:0071321  cellular response to cGMP
GO:0071260  cellular response to mechanical stimulus
GO:0046069  cGMP catabolic process
GO:0019934  cGMP-mediated signaling
GO:0008152  metabolic process
GO:0030224  monocyte differentiation
GO:0030818  negative regulation of cAMP biosynthetic process
GO:0033159  negative regulation of protein import into nucleus, translocation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0043116  negative regulation of vascular permeability
GO:0010628  positive regulation of gene expression
GO:0050729  positive regulation of inflammatory response
GO:0043117  positive regulation of vascular permeability
GO:0006626  protein targeting to mitochondrion

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0005794  Golgi apparatus
GO:0045121  membrane raft
GO:0005759  mitochondrial matrix
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0042734  presynaptic membrane

Molecular Function

GO:0030552  cAMP binding
GO:0030553  cGMP binding
GO:0004118  cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0004112  cyclic-nucleotide phosphodiesterase activity
GO:0008144  drug binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0030911  TPR domain binding