interleukin 12a

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:113.90 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_053390
Gene ID 84405
Unigene ID Rn.207199
Probe set ID -
Ensembl ID ENSRNOG00000009468

オーソログ対応遺伝子

ヒト[1]  NM_000882
マウス[2]  NM_001159424, NM_008351

染色体

2q31  [158,710,261  -  158,717,689]

遺伝子ファミリー (Interpro ID)

IPR009079  Four-helical cytokine-like, core
IPR004281  Interleukin-12 alpha subunit

Link to Pubmed  (Pubmed ID)

12471147
12697150
14681019
17056578

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0016477  cell migration
GO:0050830  defense response to Gram-positive bacterium
GO:0042832  defense response to protozoan
GO:0006955  immune response
GO:0032700  negative regulation of interleukin-17 production
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0045785  positive regulation of cell adhesion
GO:0032729  positive regulation of interferon-gamma production
GO:0050671  positive regulation of lymphocyte proliferation
GO:0032816  positive regulation of natural killer cell activation
GO:0045954  positive regulation of natural killer cell mediated cytotoxicity
GO:0002860  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0051135  positive regulation of NK T cell activation
GO:0034393  positive regulation of smooth muscle cell apoptosis
GO:0045582  positive regulation of T cell differentiation
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0042102  positive regulation of T cell proliferation
GO:0042520  positive regulation of tyrosine phosphorylation of Stat4 protein
GO:0032496  response to lipopolysaccharide
GO:0010224  response to UV-B
GO:0009615  response to virus

Cellular Component

GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0043514  interleukin-12 complex

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0042163  interleukin-12 beta subunit binding
GO:0005143  interleukin-12 receptor binding
GO:0045513  interleukin-27 binding
GO:0046982  protein heterodimerization activity