BCL2-like 11 (apoptosis facilitator)

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Synonym

BimL, BIM, Bcl2-interacting mediator of cell death, BCL2L11, BCL2-like 11 (apoptosis facilitator), BIM-beta7, BOD, BAM, BimEL, Bcl-2-like protein 11, BIM-beta6, BIM-alpha6

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:60.70 peripheral blood:54.70 spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:-
GeneChip cerebrum:4.18 cerebellum:4.31 brain stem:4.25 corpus callosum/glia:4.24 pineal gland:- peripheral nerve:4.07 spine:4.07 retina:- eye:- artery/aorta:4.11 vein:4.60 lymphnode:4.33 peripheral blood:- spleen:4.45 thymus:4.62 bone marrow:4.67 adipose:4.28 bone:- skin:4.26
CAGE cerebrum:1.84 cerebellum:- brain stem:2.00 corpus callosum/glia:2.29 pineal gland:1.77 peripheral nerve:- spine:2.36 retina:- eye:- artery/aorta:2.68 vein:3.94 lymphnode:3.81 peripheral blood:- spleen:3.99 thymus:4.06 bone marrow:- adipose:2.93 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.53 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:32.80 prostate:22.50 ovary:- testis:8.70 heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:25.40     liver/hepato:-        lung:19.60    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:97.80 breast:- salivary:-
GeneChip uterus:4.19 placenta:4.09 prostate:4.16 ovary:4.35 testis:6.08 heart:4.46 muscle:4.39 esophagus:4.40 stomach:4.27 intestine:4.43 colon:4.57 liver/hepato:4.39 lung:4.41 bladder:- kidney:4.33 pituitary:4.06 thyroid/parathyroid:4.51 adrenal gland:4.37 pancreas:4.63 breast:4.25 salivary:4.47
CAGE uterus:2.58 placenta:3.06 prostate:2.75 ovary:2.72 testis:2.57 heart:2.44 muscle:2.90 esophagus:2.79 stomach:- intestine:3.15 colon:3.22     liver/hepato:3.14    lung:2.89 bladder:2.92 kidney:3.22 pituitary:3.64 thyroid/parathyroid:3.94 adrenal gland:- pancreas:3.16 breast:3.47 salivary:2.53
RNA-seq uterus:- placenta:- prostate:1.24 ovary:1.44 testis:0.04 heart:0.23 muscle:0.89 esophagus:- stomach:- intestine:- colon:0.45     liver/hepato:0.58        lung:1.81    bladder:- kidney:0.74 pituitary:- thyroid/parathyroid:2.04 adrenal gland:0.65 pancreas:- breast:0.36 salivary:-

IDs

Refseq ID NM_138621
Gene ID 10018
Unigene ID Hs.469658
Probe set ID 222343_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000153094
GTEx ID ENSG00000153094

Orthologous Gene

Mouse[30]  NM_009754, NM_207680, NM_207681
Rat[5]  NM_022612, NM_171989, NM_207681

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

8918887
8929531
9430630
9463381
9731710
10198631
10381623
10576740
10837489
11050388
11210187
11301022
11435715
11546872
11583631
11734221
11859372
11997495
12019181
12095614
12118373
12198137
12376548
12388545
12477932
12486001
12591950
12787561
12818176
12844146
14527951
14555991
14561217
14596824
14676826
14681225
14732682
14764673
14769789
14970329
14996839
15014070
15030401
15096481
15146197
15147734
15193260
15378010
15459900
15486195
15489334
15509554
15653751
15661735
15688014
15694340
15711598
15721256
15728578
15731037
15731089
15767553
15824087
15843898
15899862
15989957
16022280
16051596
16091744
16148027
16183168
16213503
16260615
16282323
16373335
16476732
16478725
16697956
16773715
16810067
16888645
16951744
17051334
17062728
17067554
17074758
17105963
17151701
17158029
17188240
17203211
17207965
17218274
17251431
17276340
17289999
17486061
17499214
17525735
17531220
17538248
17637819
17653091
17686764
17692808
17698840
17716672
17717606
17927446
18006817
18063582
18064628
18089817
18165867
18182577
18195012
18246127
18251703
18345036
18348176
18354037
18391004
18398508
18413764
18420585
18508762
18549468
18651223
18668139
18677096
18715233
18715501
18758461
18806830
18812174
18925930
18949058
18981303
19050264
19052714
19064725
19100522
19101511
19141860
19148187
19150432
19285955
19300516
19305426
19308286
19330811
19332026
19336552
19403302
19407828
19494111
19541822
19573080
19574221
19587239
19622586
19622774
19641506
19737817
19773279
19773546
19805519
19850739
19881544
19893569
19914305
20010785
20066663
20074640
20082325
20086250
20160166
20206402
20231287
20237869
20332261
20348947
20404322
20431602
20697841
20700448
20705940
20819778
20821734
20841506
20855536
20861305
20877573
20878914
20885957
20959405
21041309
21130142
21148306
21148799
21151127
21247487
21333317
21339291
21367852
21375523
21378313
21415216
21478148
21481848
21507240
21533175
21555518
21613222
21625639
21655183
21659544
21671007
21673341
21729544
21732363
21808067
21832049
21899728
21924351
21937453
21958719
21984578
21988832
22071694
22076535
22081075
22093624
22131152
22145099
22160382
22245094
22270368
22349704
22388891
22391963
22426421
22430213
22516966
22572381
22609401
22622039
22628193
22645134
22742832
22762551
22788963
22802411
22819074
22895567
22905229
23012423
23047821
23138847
23152053
23152504
23235460
23243017
23270470
23295054
23301543
23358890
23382048
23394612
23402819
23441183
23500081
23532334
23569333
23633923
23648111
23681223
23737756
23770605
23824909
23851982
23872733
23874387
23912711
24074954
24227856
24239173
24263101
24292274
24425048
24536031
24650799

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006915  apoptosis
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0007420  brain development
GO:0007160  cell-matrix adhesion
GO:0060154  cellular process regulating host cell cycle in response to virus
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0043583  ear development
GO:0001701  in utero embryonic development
GO:0006917  induction of apoptosis
GO:0001822  kidney development
GO:0008584  male gonad development
GO:0030879  mammary gland development
GO:0002262  myeloid cell homeostasis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0042475  odontogenesis of dentine-containing tooth
GO:0048066  pigmentation during development
GO:0043065  positive regulation of apoptosis
GO:0045787  positive regulation of cell cycle
GO:0043525  positive regulation of neuron apoptosis
GO:0032464  positive regulation of protein homooligomerization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0048563  post-embryonic organ morphogenesis
GO:0046620  regulation of organ growth
GO:0048070  regulation of pigmentation during development
GO:0034976  response to endoplasmic reticulum stress
GO:0007283  spermatogenesis
GO:0048536  spleen development
GO:0043029  T cell homeostasis
GO:0048538  thymus development
GO:0035148  tube lumen formation

Cellular Component

GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0019898  extrinsic to membrane
GO:0005874  microtubule
GO:0005741  mitochondrial outer membrane

Molecular Function

GO:0008017  microtubule binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity