serine/threonine kinase 25 (STE20 homolog, yeast)

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Synonym

DKFZp686J1430, SOK1, Ste20/oxidant stress response kinase 1, STK25, YSK1, Ste20-like kinase, serine/threonine kinase 25 (STE20 homolog, yeast), Sterile 20/oxidant stress-response kinase 1, SOK-1, Serine/threonine-protein kinase 25

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:112.60 cerebellum:37.80 brain stem:- corpus callosum/glia:58.30 pineal gland:445 peripheral nerve:153.40 spine:224.60 retina:- eye:235.10 artery/aorta:- vein:66.60 lymphnode:121.30 peripheral blood:127.50 spleen:170.20 thymus:141.70 bone marrow:39.40 adipose:- bone:89.60 skin:100.80
GeneChip cerebrum:6.50 cerebellum:6.58 brain stem:6.31 corpus callosum/glia:6.20 pineal gland:- peripheral nerve:6.32 spine:6.32 retina:- eye:- artery/aorta:6.45 vein:5.88 lymphnode:6.32 peripheral blood:- spleen:6.62 thymus:6.65 bone marrow:6.07 adipose:6.41 bone:- skin:6.39
CAGE cerebrum:4.06 cerebellum:- brain stem:3.80 corpus callosum/glia:3.97 pineal gland:3.56 peripheral nerve:- spine:3.52 retina:- eye:- artery/aorta:3.79 vein:3.98 lymphnode:3.55 peripheral blood:- spleen:3.61 thymus:3.64 bone marrow:- adipose:3.77 bone:- skin:-
RNA-seq cerebrum:4.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.25 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:40.10 prostate:78.90 ovary:37.30 testis:199 heart:12.80 muscle:80.40 esophagus:- stomach:63.70 intestine:64.80 colon:59.40     liver/hepato:63.30        lung:73.30    bladder:125.60 kidney:104 pituitary:- thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:106.70 breast:37.20 salivary:328.40
GeneChip uterus:6.30 placenta:6.12 prostate:6.46 ovary:6 testis:7.12 heart:5.94 muscle:7.88 esophagus:6.61 stomach:6.12 intestine:6.58 colon:5.92 liver/hepato:5.97 lung:6.40 bladder:- kidney:6.35 pituitary:6.60 thyroid/parathyroid:7.08 adrenal gland:6.15 pancreas:5.91 breast:6.36 salivary:6.14
CAGE uterus:4.04 placenta:3.69 prostate:3.91 ovary:3.84 testis:4.03 heart:3.90 muscle:5.07 esophagus:3.94 stomach:- intestine:3.69 colon:4.14     liver/hepato:3.56    lung:3.62 bladder:3.70 kidney:3.65 pituitary:3.42 thyroid/parathyroid:3.96 adrenal gland:- pancreas:3.99 breast:3.80 salivary:3.52
RNA-seq uterus:- placenta:- prostate:4.55 ovary:4.57 testis:4.57 heart:3.70 muscle:6.54 esophagus:- stomach:- intestine:- colon:3.91     liver/hepato:3.37        lung:3.93    bladder:- kidney:4.31 pituitary:- thyroid/parathyroid:5.24 adrenal gland:4.37 pancreas:- breast:4.44 salivary:-

Gene Information

IDs

Refseq ID NM_006374
Gene ID 10494
Unigene ID Hs.516807
Probe set ID 201314_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000115694
GTEx ID ENSG00000115694

Orthologous Gene

Mouse[1]  NM_021537
Rat [0]  

Chromosomal Region

2q37.3  [242,432,089  -  242,449,145]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8887545
8889548
9160885
12477932
14702039
15037601
15489334
15815621
16189514
16344560
17253963
17353931
17657516
18364353
18782753
19615732
19953087
20098747
20360068
20592472
20949042
21139048
21396913
21832049
21900206
21906983
22391949
22505724
22652780
22782892
22939629
23000965
23455922
23535732
23889253
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0007163  establishment or maintenance of cell polarity
GO:0051645  Golgi localization
GO:0050772  positive regulation of axonogenesis
GO:0006979  response to oxidative stress
GO:0007165  signal transduction

Cellular Component

GO:0005794  Golgi apparatus

Molecular Function

GO:0005524  ATP binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity