protein tyrosine phosphatase, non-receptor type 21

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Synonym

PTPD1, PTPN21, Tyrosine-protein phosphatase non-receptor type 21, PTPRL10, Protein-tyrosine phosphatase D1, protein tyrosine phosphatase, non-receptor type 21

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:153.40 spine:- retina:- eye:47 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:25.60 skin:52.80
GeneChip cerebrum:4.78 cerebellum:4.94 brain stem:4.82 corpus callosum/glia:4.82 pineal gland:- peripheral nerve:4.97 spine:4.78 retina:- eye:- artery/aorta:5.53 vein:5.50 lymphnode:4.63 peripheral blood:- spleen:4.51 thymus:4.27 bone marrow:4.74 adipose:5.54 bone:- skin:5.86
CAGE cerebrum:1.35 cerebellum:- brain stem:1.63 corpus callosum/glia:2.16 pineal gland:1.17 peripheral nerve:- spine:1.65 retina:- eye:- artery/aorta:2.93 vein:1.95 lymphnode:0.93 peripheral blood:- spleen:1.24 thymus:0.37 bone marrow:- adipose:2.14 bone:- skin:-
RNA-seq cerebrum:1.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.19 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:69.20 prostate:11.30 ovary:- testis:47.60 heart:63.90 muscle:20.10 esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:10.60        lung:14.70    bladder:125.60 kidney:20.80 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:18.60 salivary:-
GeneChip uterus:5.23 placenta:5.99 prostate:5.03 ovary:5.10 testis:6.57 heart:5.62 muscle:5.45 esophagus:5.41 stomach:5.23 intestine:5.02 colon:5.37 liver/hepato:5.07 lung:5.58 bladder:- kidney:5.06 pituitary:4.67 thyroid/parathyroid:5.21 adrenal gland:4.96 pancreas:4.72 breast:4.96 salivary:4.98
CAGE uterus:2.26 placenta:2.93 prostate:2.22 ovary:2.19 testis:2.22 heart:2.35 muscle:1.64 esophagus:1.93 stomach:- intestine:2.10 colon:2.11     liver/hepato:1.25    lung:2.49 bladder:2.27 kidney:1.90 pituitary:0.99 thyroid/parathyroid:2.23 adrenal gland:- pancreas:1.74 breast:2.59 salivary:1.49
RNA-seq uterus:- placenta:- prostate:2.86 ovary:3.44 testis:3.61 heart:3.24 muscle:1.95 esophagus:- stomach:- intestine:- colon:3.14     liver/hepato:1.03        lung:3.07    bladder:- kidney:2.84 pituitary:- thyroid/parathyroid:3.54 adrenal gland:1.95 pancreas:- breast:3.40 salivary:-

Gene Information

IDs

Refseq ID NM_007039
Gene ID 11099
Unigene ID Hs.437040
Probe set ID 205438_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000070778
GTEx ID ENSG00000070778

Orthologous Gene

Mouse[4]  NM_001146199, NM_011877
Rat [0]  

Chromosomal Region

14q31.3  [88,932,122  -  89,021,077]

Gene Family (Interpro ID)

IPR019749  Band 4.1 domain
IPR019750  Band 4.1 subgroup
IPR000242  Protein-tyrosine phosphatase, receptor/non-receptor type

Link to Pubmed  (Pubmed ID)

7519780
7838537
8889548
9685376
10585123
11013262
12477932
15143158
16344560
16918960
18223254
19000305
20923765
21752600

Gene Ontology  (GO ID)

Biological Process

GO:0006470  protein amino acid dephosphorylation

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton

Molecular Function

GO:0004725  protein tyrosine phosphatase activity