frizzled homolog 10 (Drosophila)

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Synonym

frizzled (Drosophila) homolog 10, FZD10, FzE7, Frizzled-10 precursor, FZ-10, frizzled homolog 10 (Drosophila), hFz10, Fz-10

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:-
GeneChip cerebrum:3.66 cerebellum:3.83 brain stem:3.81 corpus callosum/glia:3.61 pineal gland:- peripheral nerve:3.80 spine:3.77 retina:- eye:- artery/aorta:3.65 vein:3.85 lymphnode:4.36 peripheral blood:- spleen:3.24 thymus:3.43 bone marrow:3.49 adipose:4.02 bone:- skin:5.80
CAGE cerebrum:0.91 cerebellum:- brain stem:1.09 corpus callosum/glia:1.34 pineal gland:1.46 peripheral nerve:- spine:1.00 retina:- eye:- artery/aorta:0.59 vein:0.96 lymphnode:1.90 peripheral blood:- spleen:0.09 thymus:0.68 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:- salivary:-
GeneChip uterus:4.86 placenta:4.95 prostate:4.93 ovary:3.99 testis:3.42 heart:3.51 muscle:3.76 esophagus:7.18 stomach:3.85 intestine:3.68 colon:4 liver/hepato:3.52 lung:3.80 bladder:- kidney:3.49 pituitary:3.65 thyroid/parathyroid:3.94 adrenal gland:3.62 pancreas:3.55 breast:4.51 salivary:4.07
CAGE uterus:2.05 placenta:2.39 prostate:1.77 ovary:1.69 testis:0.48 heart:0.46 muscle:0.42 esophagus:3.45 stomach:- intestine:0.61 colon:0.24     liver/hepato:0    lung:1.34 bladder:1.89 kidney:0.08 pituitary:0.90 thyroid/parathyroid:1.15 adrenal gland:- pancreas:0.94 breast:0 salivary:1.28
RNA-seq uterus:- placenta:- prostate:0.72 ovary:1.07 testis:0.48 heart:0.05 muscle:0.14 esophagus:- stomach:- intestine:- colon:0.17     liver/hepato:0        lung:0.43    bladder:- kidney:0.10 pituitary:- thyroid/parathyroid:0.61 adrenal gland:1.03 pancreas:- breast:0.50 salivary:-

Gene Information

IDs

Refseq ID NM_007197
Gene ID 11211
Unigene ID Hs.31664
Probe set ID 219764_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111432
GTEx ID ENSG00000111432

Orthologous Gene

Mouse[1]  NM_175284
Rat[1]  NM_175284

Chromosomal Region

12q24.33  [130,647,004  -  130,650,285]

Gene Family (Interpro ID)

IPR000539  Frizzled protein
IPR020067  Frizzled-like domain
IPR017981  GPCR, family 2-like

Link to Pubmed  (Pubmed ID)

9707618
10448064
11597177
11786918
12477932
15489334
15930302
16007199
18271942
19134005
19137009
20037267
20227380
20634891
22780124

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0071300  cellular response to retinoic acid
GO:0009790  embryonic development
GO:0008406  gonad development
GO:0034259  negative regulation of Rho GTPase activity
GO:0030182  neuron differentiation
GO:0043507  positive regulation of JUN kinase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0032956  regulation of actin cytoskeleton organization
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0042995  cell projection
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding