cholinergic receptor, muscarinic 3

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Synonym

HM3, cholinergic receptor, muscarinic 3, Muscarinic acetylcholine receptor M3, CHRM3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:6.62

cerebellum:4.60

brain stem:5.52

corpus callosum/glia:4.91

pineal gland:-

peripheral nerve:4.96

spine:5.16

retina:-

eye:-

artery/aorta:5.03

vein:4.69

lymphnode:4.52

peripheral blood:-

spleen:4.70

thymus:4.78

bone marrow:4.64

adipose:4.75

bone:-

skin:5.08

CAGE

cerebrum:2.74

cerebellum:-

brain stem:1.51

corpus callosum/glia:1.25

pineal gland:1.78

peripheral nerve:-

spine:1.33

retina:-

eye:-

artery/aorta:1.43

vein:0

lymphnode:0.95

peripheral blood:-

spleen:0.80

thymus:0.18

bone marrow:-

adipose:1.01

bone:-

skin:-

RNA-seq

cerebrum:1.98

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.18

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.21

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:4.84

placenta:4.75

prostate:5.09

ovary:5.40

testis:4.56

heart:4.74

muscle:4.85

esophagus:5.30

stomach:6.94

intestine:6.31

colon:5.41

liver/hepato:4.48

lung:5.19

bladder:-

kidney:5.22

pituitary:4.89

thyroid/parathyroid:5.32

adrenal gland:4.93

pancreas:7.50

breast:4.77

salivary:8.19

CAGE

uterus:1.36

placenta:0.37

prostate:2.86

ovary:2.70

testis:1.39

heart:0.35

muscle:0.09

esophagus:2.30

stomach:-

intestine:2.10

colon:2.54

liver/hepato:0.78

lung:1.41

bladder:3.00

kidney:0.78

pituitary:1.31

thyroid/parathyroid:0.93

adrenal gland:-

pancreas:3.40

breast:0.55

salivary:4.38

RNA-seq

uterus:-

placenta:-

prostate:3.11

ovary:1.91

testis:1.06

heart:0.05

muscle:0.03

esophagus:-

stomach:-

intestine:-

colon:1.41

liver/hepato:0.24

lung:0.33

bladder:-

kidney:0.38

pituitary:-

thyroid/parathyroid:0.38

adrenal gland:0.09

pancreas:-

breast:0.13

salivary:-

IDs

Refseq ID	NM_000740
Gene ID	1131
Unigene ID	-
Probe set ID	214596_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000133019
GTEx ID	ENSG00000133019

Orthologous Gene

Mouse[1]	NM_033269
Rat [0]

Chromosomal Region

1q43 [239,549,865 - 240,078,750]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR000995	Muscarinic acetylcholine receptor
IPR001183	Muscarinic acetylcholine receptor M3

Gene Ontology (GO ID)

Biological Process

GO:0008283	cell proliferation
GO:0006112	energy reserve metabolic process
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007399	nervous system development
GO:0045987	positive regulation of smooth muscle contraction
GO:0006464	protein modification process
GO:0050796	regulation of insulin secretion
GO:0003056	regulation of vascular smooth muscle contraction
GO:0046541	saliva secretion
GO:0007165	signal transduction
GO:0006939	smooth muscle contraction

Cellular Component

GO:0032279	asymmetric synapse
GO:0016323	basolateral plasma membrane
GO:0030054	cell junction
GO:0030425	dendrite
GO:0005887	integral to plasma membrane
GO:0043679	nerve terminal
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane

Molecular Function

GO:0042166	acetylcholine binding
GO:0008144	drug binding
GO:0016907	G-protein coupled acetylcholine receptor activity
GO:0004435	phosphoinositide phospholipase C activity
GO:0004872	receptor activity

cholinergic receptor, muscarinic 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function