activating transcription factor 2

Synonym

cAMP response element-binding protein CRE-BP1, Activating transcription factor 2, ATF2, activating transcription factor 2, CRE-BP1, MGC111558, CREBP1, HB16, CREB2, Cyclic AMP-dependent transcription factor ATF-2, TREB7

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:54.50

cerebellum:100.80

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:-

spine:336.90

retina:118.60

eye:41.10

artery/aorta:-

vein:133.30

lymphnode:10.10

peripheral blood:18.20

spleen:94.50

thymus:25.80

bone marrow:39.40

adipose:-

bone:64

skin:48

GeneChip

cerebrum:6.41

cerebellum:6.43

brain stem:6.66

corpus callosum/glia:5.95

pineal gland:-

peripheral nerve:6.48

spine:6.26

retina:-

eye:-

artery/aorta:6.10

vein:6.01

lymphnode:5.94

peripheral blood:-

spleen:6.31

thymus:7.36

bone marrow:5.48

adipose:6.15

bone:-

skin:5.78

CAGE

cerebrum:4.16

cerebellum:-

brain stem:4.29

corpus callosum/glia:4.10

pineal gland:3.98

peripheral nerve:-

spine:4.16

retina:-

eye:-

artery/aorta:3.83

vein:3.82

lymphnode:3.81

peripheral blood:-

spleen:4.05

thymus:4.54

bone marrow:-

adipose:4.42

bone:-

skin:-

RNA-seq

cerebrum:3.58

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.86

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.73

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:43.70

prostate:33.80

ovary:-

testis:69.20

heart:51.10

muscle:-

esophagus:-

stomach:21.20

intestine:97.20

colon:33.90

liver/hepato:42.20

lung:73.30

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:152.40

pancreas:71.10

breast:92.90

salivary:-

GeneChip

uterus:6.93

placenta:5.45

prostate:6.71

ovary:6.70

testis:5.84

heart:5.60

muscle:5.94

esophagus:5.02

stomach:5.87

intestine:5.95

colon:5.14

liver/hepato:5.72

lung:5.98

bladder:-

kidney:5.85

pituitary:6.14

thyroid/parathyroid:6.79

adrenal gland:6.12

pancreas:5.24

breast:6.30

salivary:5.51

CAGE

uterus:4.37

placenta:3.82

prostate:4.10

ovary:4.31

testis:3.95

heart:3.54

muscle:3.46

esophagus:3.97

stomach:-

intestine:3.68

colon:3.43

liver/hepato:4.04

lung:3.96

bladder:4.28

kidney:4.10

pituitary:4.47

thyroid/parathyroid:4.30

adrenal gland:-

pancreas:3.40

breast:3.71

salivary:3.83

RNA-seq

uterus:-

placenta:-

prostate:3.75

ovary:3.82

testis:3.32

heart:2.23

muscle:1.45

esophagus:-

stomach:-

intestine:-

colon:3.18

liver/hepato:1.45

lung:3.15

bladder:-

kidney:3.24

pituitary:-

thyroid/parathyroid:3.41

adrenal gland:2.47

pancreas:-

breast:2.58

salivary:-

IDs

Refseq ID	NM_001880
Gene ID	1386
Unigene ID	Hs.592510
Probe set ID	212984_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000115966
GTEx ID	ENSG00000115966

Orthologous Gene

Mouse[8]	NM_001025093, NM_009715
Rat [0]

Chromosomal Region

2q31.1 [175,936,978 - 176,033,110]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004827	Basic-leucine zipper (bZIP) transcription factor
IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type

Gene Ontology (GO ID)

Biological Process

GO:0060612	adipose tissue development
GO:0045444	fat cell differentiation
GO:0016573	histone acetylation
GO:0045087	innate immune response
GO:0031573	intra-S DNA damage checkpoint
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0003151	outflow tract morphogenesis
GO:0051091	positive regulation of transcription factor activity
GO:0032915	positive regulation of transforming growth factor-beta2 production
GO:0051090	regulation of transcription factor activity
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0006974	response to DNA damage stimulus
GO:0006970	response to osmotic stress
GO:0051403	stress-activated MAPK cascade
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0005741	mitochondrial outer membrane
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0008140	cAMP response element binding protein binding
GO:0003682	chromatin binding
GO:0004402	histone acetyltransferase activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0019901	protein kinase binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0003713	transcription coactivator activity
GO:0003700	transcription factor activity

activating transcription factor 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function