DENN/MADD domain containing 5B

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Synonym

MGC24039, FLJ43333, FLJ41648, DKFZp686P1174

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:-
GeneChip cerebrum:5.29 cerebellum:5.68 brain stem:5.16 corpus callosum/glia:4.47 pineal gland:- peripheral nerve:4.51 spine:4.77 retina:- eye:- artery/aorta:4 vein:3.90 lymphnode:4.45 peripheral blood:- spleen:4.78 thymus:3.56 bone marrow:3.56 adipose:3.82 bone:- skin:3.59
CAGE cerebrum:3.83 cerebellum:- brain stem:3.51 corpus callosum/glia:3.45 pineal gland:4.04 peripheral nerve:- spine:3.22 retina:- eye:- artery/aorta:3.38 vein:3.02 lymphnode:2.95 peripheral blood:- spleen:3.31 thymus:1.58 bone marrow:- adipose:2.98 bone:- skin:-
RNA-seq cerebrum:2.96 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.52 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:- ovary:- testis:4.30 heart:38.30 muscle:- esophagus:- stomach:21.20 intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.07 placenta:3.51 prostate:3.46 ovary:4.69 testis:5.31 heart:4.67 muscle:4.26 esophagus:3.52 stomach:4.06 intestine:3.90 colon:3.67 liver/hepato:4.73 lung:3.71 bladder:- kidney:4.31 pituitary:4.97 thyroid/parathyroid:3.54 adrenal gland:4.71 pancreas:4.16 breast:3.83 salivary:3.43
CAGE uterus:3.27 placenta:2.16 prostate:2.76 ovary:3.90 testis:3.80 heart:3.67 muscle:3.28 esophagus:2.57 stomach:- intestine:3.92 colon:3.16     liver/hepato:3.28    lung:2.31 bladder:3.07 kidney:2.80 pituitary:3.53 thyroid/parathyroid:2.40 adrenal gland:- pancreas:2.76 breast:3.19 salivary:1.75
RNA-seq uterus:- placenta:- prostate:1.81 ovary:3.29 testis:2.85 heart:2.97 muscle:2.01 esophagus:- stomach:- intestine:- colon:1.63     liver/hepato:1.88        lung:1.31    bladder:- kidney:1.52 pituitary:- thyroid/parathyroid:1.39 adrenal gland:1.91 pancreas:- breast:1.66 salivary:-

Gene Information

IDs

Refseq ID NM_144973
Gene ID 160518
Unigene ID Hs.118166
Probe set ID 215058_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170456
GTEx ID ENSG00000170456

Orthologous Gene

Mouse[1]  NM_177192
Rat[1]  NM_177192

Chromosomal Region

12p11.21  [31,535,157  -  31,744,031]

Gene Family (Interpro ID)

IPR008976  Lipase/lipooxygenase, PLAT/LH2
IPR001024  Lipoxygenase, LH2

Link to Pubmed  (Pubmed ID)

8889548
12477932
14702039
21906983
21963094
22939629
23000965

Gene Ontology  (GO ID)

Biological Process

GO:0050982  detection of mechanical stimulus

Cellular Component

GO:0016021  integral to membrane
GO:0016020  membrane

Molecular Function

GO:0005262  calcium channel activity
GO:0017112  Rab guanyl-nucleotide exchange factor activity