cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)

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Synonym

MEGF3, CDHF10, FLJ42737, Epidermal growth factor-like 2, KIAA0279, Flamingo 1, EGF LAG seven-pass G-type receptor 2, Flamingo1, EGFL2, FLJ34118, CELSR2, FLJ45143, Multiple epidermal growth factor-like domains 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:135.10 cerebellum:113.30 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:64.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:14.40
GeneChip cerebrum:7.90 cerebellum:6.96 brain stem:7.54 corpus callosum/glia:7.90 pineal gland:- peripheral nerve:6.89 spine:7.59 retina:- eye:- artery/aorta:5.69 vein:5.30 lymphnode:5.80 peripheral blood:- spleen:5.45 thymus:5.57 bone marrow:5.42 adipose:5.74 bone:- skin:6.83
CAGE cerebrum:3.68 cerebellum:- brain stem:3.98 corpus callosum/glia:4.30 pineal gland:1.62 peripheral nerve:- spine:3.65 retina:- eye:- artery/aorta:1.16 vein:1.29 lymphnode:1.35 peripheral blood:- spleen:0.32 thymus:1.10 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:3.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.80 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.41 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:7.30 prostate:- ovary:- testis:47.60 heart:25.50 muscle:40.20 esophagus:- stomach:42.50 intestine:- colon:17     liver/hepato:-        lung:-    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:204.40 salivary:-
GeneChip uterus:5.83 placenta:5.55 prostate:6.02 ovary:6.10 testis:7.16 heart:5.45 muscle:5.85 esophagus:7.04 stomach:5.47 intestine:5.42 colon:5.88 liver/hepato:5.31 lung:5.27 bladder:- kidney:6.67 pituitary:6.34 thyroid/parathyroid:7.22 adrenal gland:5.56 pancreas:5.31 breast:7.04 salivary:6.20
CAGE uterus:1.96 placenta:0.68 prostate:1.64 ovary:1.29 testis:2.86 heart:0.97 muscle:1.57 esophagus:2.48 stomach:- intestine:0.48 colon:1.58     liver/hepato:0.78    lung:1.30 bladder:1.18 kidney:1.90 pituitary:1.15 thyroid/parathyroid:2.41 adrenal gland:- pancreas:0.94 breast:0.90 salivary:1.82
RNA-seq uterus:- placenta:- prostate:1.53 ovary:1.40 testis:2.35 heart:0.98 muscle:1.42 esophagus:- stomach:- intestine:- colon:0.85     liver/hepato:0.77        lung:0.45    bladder:- kidney:2.14 pituitary:- thyroid/parathyroid:2.30 adrenal gland:0.41 pancreas:- breast:1.19 salivary:-

Gene Information

IDs

Refseq ID NM_001408
Gene ID 1952
Unigene ID Hs.57652
Probe set ID 204029_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143126
GTEx ID ENSG00000143126

Orthologous Gene

Mouse[4]  NM_001004177, NM_017392
Rat [0]  

Chromosomal Region

1p13.3  [109,792,641  -  109,818,377]

Gene Family (Interpro ID)

IPR002126  Cadherin
IPR015919  Cadherin-like
IPR008985  Concanavalin A-like lectin/glucanase
IPR013320  Concanavalin A-like lectin/glucanase, subgroup
IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3
IPR000832  GPCR, family 2, secretin-like
IPR017981  GPCR, family 2-like
IPR001791  Laminin G

Link to Pubmed  (Pubmed ID)

9039502
9693030
10380929
10716726
10907856
14702039
16169070
17474147
18179892
18193043
18193044
18262040
18649068
19060906
19060910
19060911
19198609
19299407
19487539
19913121
19936222
20031591
20167577
20339536
20370913
20442857
20570916
20571754
20628086
20679960
20686565
20691829
20738937
20864672
20971364
21087763
21347282
21378988
21875946
21906983
21909109
21943158
21963094
22003152
23118302
24097068

Gene Ontology  (GO ID)

Biological Process

GO:0033326  cerebrospinal fluid secretion
GO:0042384  cilium assembly
GO:0003341  cilium movement
GO:0048813  dendrite morphogenesis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007156  homophilic cell adhesion
GO:0021999  neural plate anterior/posterior pattern formation
GO:0001764  neuron migration
GO:0007218  neuropeptide signaling pathway
GO:0022407  regulation of cell-cell adhesion
GO:0032880  regulation of protein localization
GO:0006355  regulation of transcription, DNA-dependent
GO:0021591  ventricular system development
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0004930  G-protein coupled receptor activity