eukaryotic translation termination factor 1

Synonym

ERF, eRF1, ETF1, TB3-1, Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, SUP45L1, Cl1 protein, D5S1995, RF1, eukaryotic translation termination factor 1, MGC111066

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:67.60

cerebellum:37.80

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:-

spine:-

retina:118.60

eye:64.60

artery/aorta:149.90

vein:66.60

lymphnode:70.80

peripheral blood:145.70

spleen:113.40

thymus:103.10

bone marrow:393.60

adipose:80.70

bone:89.60

skin:105.60

GeneChip

cerebrum:6.29

cerebellum:5.82

brain stem:6.32

corpus callosum/glia:6.08

pineal gland:-

peripheral nerve:6.68

spine:6.44

retina:-

eye:-

artery/aorta:7.31

vein:7.04

lymphnode:7

peripheral blood:-

spleen:6.53

thymus:6.84

bone marrow:7.20

adipose:7.44

bone:-

skin:8.31

CAGE

cerebrum:3.46

cerebellum:-

brain stem:3.64

corpus callosum/glia:3.48

pineal gland:3.31

peripheral nerve:-

spine:3.58

retina:-

eye:-

artery/aorta:3.61

vein:3.69

lymphnode:3.47

peripheral blood:-

spleen:3.57

thymus:3.44

bone marrow:-

adipose:3.75

bone:-

skin:-

RNA-seq

cerebrum:4.46

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.40

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.29

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:145.80

placenta:109.30

prostate:101.40

ovary:186.30

testis:134.10

heart:76.60

muscle:-

esophagus:-

stomach:42.50

intestine:32.40

colon:42.40

liver/hepato:73.90

lung:92.90

bladder:-

kidney:124.80

pituitary:-

thyroid/parathyroid:327.50

adrenal gland:101.60

pancreas:71.10

breast:46.50

salivary:328.40

GeneChip

uterus:7.01

placenta:7.62

prostate:7.71

ovary:6.78

testis:7.61

heart:6.93

muscle:8.06

esophagus:8.40

stomach:6.84

intestine:7.14

colon:6.56

liver/hepato:6.67

lung:7.66

bladder:-

kidney:6.90

pituitary:6.88

thyroid/parathyroid:6.82

adrenal gland:6.90

pancreas:6.77

breast:7.54

salivary:7.11

CAGE

uterus:3.68

placenta:4.15

prostate:3.67

ovary:3.92

testis:3.97

heart:4.00

muscle:3.81

esophagus:4.02

stomach:-

intestine:3.45

colon:3.25

liver/hepato:3.69

lung:3.66

bladder:3.84

kidney:3.76

pituitary:3.83

thyroid/parathyroid:3.85

adrenal gland:-

pancreas:3.61

breast:3.81

salivary:3.68

RNA-seq

uterus:-

placenta:-

prostate:4.30

ovary:4.99

testis:4.92

heart:4.31

muscle:5.50

esophagus:-

stomach:-

intestine:-

colon:5.09

liver/hepato:3.30

lung:5.25

bladder:-

kidney:4.64

pituitary:-

thyroid/parathyroid:5.59

adrenal gland:4.72

pancreas:-

breast:5.49

salivary:-

IDs

Refseq ID	NM_004730
Gene ID	2107
Unigene ID	Hs.483494
Probe set ID	201573_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000120705
GTEx ID	ENSG00000120705

Orthologous Gene

Mouse[6]	NM_144866
Rat[1]	NM_001008344

Chromosomal Region

5q31.2 [137,841,784 - 137,878,989]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004403

Peptide chain release factor eRF1/aRF1

GO:0044267	cellular protein metabolic process
GO:0010467	gene expression
GO:0016071	mRNA metabolic process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006479	protein amino acid methylation
GO:0006449	regulation of translational termination
GO:0016070	RNA metabolic process
GO:0006412	translation
GO:0006415	translational termination

GO:0005737	cytoplasm
GO:0005829	cytosol

GO:0005515	protein binding
GO:0043022	ribosome binding
GO:0003723	RNA binding
GO:0003747	translation release factor activity
GO:0016149	translation release factor activity, codon specific
GO:0008079	translation termination factor activity

eukaryotic translation termination factor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function