Rho guanine nucleotide exchange factor (GEF) 15

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Synonym

Rho guanine nucleotide exchange factor 15, Rho guanine nucleotide exchange factor (GEF) 15, MGC44868, ARGEF15, KIAA0915, FLJ13791, ARHGEF15, Vsm-RhoGEF

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:47 artery/aorta:- vein:666.50 lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:80.70 bone:12.80 skin:9.60
GeneChip cerebrum:5.43 cerebellum:5.33 brain stem:5.53 corpus callosum/glia:5.21 pineal gland:- peripheral nerve:5.53 spine:5.41 retina:- eye:- artery/aorta:6.52 vein:6.36 lymphnode:5.71 peripheral blood:- spleen:5.70 thymus:5.23 bone marrow:5.66 adipose:6.87 bone:- skin:6.33
CAGE cerebrum:1.50 cerebellum:- brain stem:1.58 corpus callosum/glia:1.73 pineal gland:1.46 peripheral nerve:- spine:1.04 retina:- eye:- artery/aorta:2.88 vein:3.11 lymphnode:1.86 peripheral blood:- spleen:2.62 thymus:0.88 bone marrow:- adipose:4.53 bone:- skin:-
RNA-seq cerebrum:0.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.54 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.16 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:69.20 prostate:22.50 ovary:- testis:21.60 heart:89.40 muscle:- esophagus:- stomach:21.20 intestine:- colon:-     liver/hepato:21.10        lung:58.70    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:327.50 adrenal gland:101.60 pancreas:26.70 breast:27.90 salivary:-
GeneChip uterus:5.84 placenta:5.67 prostate:5.61 ovary:5.52 testis:5.58 heart:6.57 muscle:6.09 esophagus:5.77 stomach:5.85 intestine:5.79 colon:5.88 liver/hepato:5.66 lung:6.85 bladder:- kidney:6.08 pituitary:5.49 thyroid/parathyroid:5.84 adrenal gland:6.05 pancreas:5.74 breast:6.02 salivary:5.71
CAGE uterus:3.39 placenta:3.03 prostate:2.93 ovary:2.66 testis:1.52 heart:3.73 muscle:3.41 esophagus:2.41 stomach:- intestine:1.99 colon:2.07     liver/hepato:2.08    lung:3.40 bladder:2.94 kidney:2.69 pituitary:1.55 thyroid/parathyroid:2.22 adrenal gland:- pancreas:1.87 breast:3.49 salivary:1.67
RNA-seq uterus:- placenta:- prostate:1.86 ovary:0.94 testis:0.22 heart:1.56 muscle:0.23 esophagus:- stomach:- intestine:- colon:2.11     liver/hepato:0.62        lung:1.72    bladder:- kidney:1.00 pituitary:- thyroid/parathyroid:0.72 adrenal gland:1.67 pancreas:- breast:1.75 salivary:-

Gene Information

IDs

Refseq ID NM_173728
Gene ID 22899
Unigene ID Hs.443109
Probe set ID 205507_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198844
GTEx ID ENSG00000198844

Orthologous Gene

Mouse[1]  NM_177566
Rat[1]  NM_001105789

Chromosomal Region

17p13.1  [8,213,559  -  8,225,834]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10048485
12168954
12477932
12775584
14702039
15489334
15604093
16189514
16344560
19911011
21029857
21029865
23029280

Gene Ontology  (GO ID)

Biological Process

GO:0050790  regulation of catalytic activity
GO:0035023  regulation of Rho protein signal transduction

Cellular Component

GO:0030425  dendrite

Molecular Function

GO:0005096  GTPase activator activity
GO:0005515  protein binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity