MCF.2 cell line derived transforming sequence-like 2

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Synonym

KIAA0861, DKFZp686K0690, FLJ42509, MCF2L2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:30 vein:- lymphnode:- peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:19.70 adipose:- bone:- skin:9.60
GeneChip cerebrum:2.66 cerebellum:2.54 brain stem:2.64 corpus callosum/glia:2.51 pineal gland:- peripheral nerve:2.57 spine:2.59 retina:- eye:- artery/aorta:2.39 vein:2.45 lymphnode:2.48 peripheral blood:- spleen:2.50 thymus:2.45 bone marrow:2.47 adipose:2.42 bone:- skin:2.39
CAGE cerebrum:3.25 cerebellum:- brain stem:2.94 corpus callosum/glia:2.67 pineal gland:3.30 peripheral nerve:- spine:2.59 retina:- eye:- artery/aorta:0.59 vein:0 lymphnode:0.78 peripheral blood:- spleen:1.83 thymus:0.37 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.14 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:32.80 prostate:22.50 ovary:- testis:21.60 heart:- muscle:40.20 esophagus:- stomach:- intestine:32.40 colon:50.90     liver/hepato:10.60        lung:107.50    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:27.90 salivary:-
GeneChip uterus:2.48 placenta:2.43 prostate:2.47 ovary:2.43 testis:2.45 heart:2.42 muscle:2.53 esophagus:2.43 stomach:2.39 intestine:2.44 colon:2.44 liver/hepato:2.48 lung:2.47 bladder:- kidney:2.43 pituitary:2.64 thyroid/parathyroid:2.42 adrenal gland:2.69 pancreas:2.50 breast:2.45 salivary:2.43
CAGE uterus:0.58 placenta:0.08 prostate:1.14 ovary:0.32 testis:0.80 heart:0.38 muscle:0.38 esophagus:0.73 stomach:- intestine:0 colon:0.56     liver/hepato:0.26    lung:0.22 bladder:0.58 kidney:0.21 pituitary:3.10 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.17 ovary:0.04 testis:0.47 heart:0.01 muscle:0.04 esophagus:- stomach:- intestine:- colon:0.18     liver/hepato:0.00        lung:0.09    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:0.10 adrenal gland:0.14 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_015078
Gene ID 23101
Unigene ID Hs.208267
Probe set ID 215112_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000053524
GTEx ID ENSG00000053524

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

3q27.1  [182,895,831  -  183,146,566]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology
IPR018159  Spectrin/alpha-actinin

Link to Pubmed  (Pubmed ID)

10048485
12421765
12477932
16344560
18259684
19343720
19648752
20379614
20667095

Gene Ontology  (GO ID)

Biological Process

GO:0035023  regulation of Rho protein signal transduction

Molecular Function

GO:0005543  phospholipid binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity