inducible T-cell co-stimulator ligand

Synonym

ICOSL, KIAA0653, CD275 antigen, B7 homolog 2, inducible T-cell co-stimulator ligand, CD275, B7-like protein Gl50, B7H2, B7-H2, ICOSLG, B7RP1, B7RP-1, LICOS, GL50, ICOS-L, B7-related protein 1, ICOS ligand precursor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:22.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:118.60

eye:17.60

artery/aorta:-

vein:-

lymphnode:40.40

peripheral blood:36.40

spleen:-

thymus:12.90

bone marrow:-

adipose:-

bone:38.40

skin:14.40

GeneChip

cerebrum:3.53

cerebellum:3.52

brain stem:3.60

corpus callosum/glia:3.54

pineal gland:-

peripheral nerve:3.32

spine:3.44

retina:-

eye:-

artery/aorta:3.55

vein:3.62

lymphnode:3.43

peripheral blood:-

spleen:3.18

thymus:3.31

bone marrow:3.42

adipose:3.52

bone:-

skin:3.77

CAGE

cerebrum:2.90

cerebellum:-

brain stem:3.66

corpus callosum/glia:4.28

pineal gland:0.95

peripheral nerve:-

spine:3.27

retina:-

eye:-

artery/aorta:2.10

vein:3.07

lymphnode:2.86

peripheral blood:-

spleen:2.36

thymus:1.90

bone marrow:-

adipose:2.33

bone:-

skin:-

RNA-seq

cerebrum:2.75

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.15

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.48

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:-

prostate:11.30

ovary:-

testis:13

heart:25.50

muscle:-

esophagus:-

stomach:63.70

intestine:-

colon:33.90

liver/hepato:10.60

lung:9.80

bladder:-

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.32

placenta:3.28

prostate:3.40

ovary:3.29

testis:3.44

heart:3.44

muscle:3.62

esophagus:3.41

stomach:3.19

intestine:3.38

colon:3.51

liver/hepato:3.40

lung:3.46

bladder:-

kidney:3.31

pituitary:3.39

thyroid/parathyroid:3.29

adrenal gland:3.28

pancreas:3.65

breast:3.34

salivary:3.33

CAGE

uterus:2.07

placenta:1.76

prostate:2.29

ovary:1.35

testis:1.83

heart:2.14

muscle:1.55

esophagus:1.96

stomach:-

intestine:2.38

colon:2.02

liver/hepato:1.60

lung:2.29

bladder:2.08

kidney:2.83

pituitary:1.26

thyroid/parathyroid:1.70

adrenal gland:-

pancreas:2.34

breast:2.41

salivary:2.22

RNA-seq

uterus:-

placenta:-

prostate:1.55

ovary:1.01

testis:1.87

heart:1.16

muscle:0.34

esophagus:-

stomach:-

intestine:-

colon:1.09

liver/hepato:0.77

lung:1.26

bladder:-

kidney:2.08

pituitary:-

thyroid/parathyroid:2.31

adrenal gland:1.52

pancreas:-

breast:0.88

salivary:-

IDs

Refseq ID	NM_015259
Gene ID	23308
Unigene ID	Hs.14155
Probe set ID	211199_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000160223
GTEx ID	ENSG00000160223

Orthologous Gene

Mouse[1]	NM_015790
Rat[1]	NM_015790

GO:0042113	B cell activation
GO:0006952	defense response
GO:0006972	hyperosmotic response
GO:0042104	positive regulation of activated T cell proliferation
GO:0045404	positive regulation of interleukin-4 biosynthetic process
GO:0007165	signal transduction
GO:0042110	T cell activation
GO:0031295	T cell costimulation

GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane

inducible T-cell co-stimulator ligand

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function