6-phosphogluconolactonase

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Synonym

6PGL, 6-phosphogluconolactonase, PGLS

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:58.80 artery/aorta:30 vein:66.60 lymphnode:182 peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:80.70 bone:- skin:4.80
GeneChip cerebrum:6.14 cerebellum:5.60 brain stem:6.34 corpus callosum/glia:6.60 pineal gland:- peripheral nerve:6.66 spine:6.56 retina:- eye:- artery/aorta:6.86 vein:6.39 lymphnode:7.28 peripheral blood:- spleen:7.06 thymus:7.24 bone marrow:7.11 adipose:7.17 bone:- skin:7.57
CAGE cerebrum:2.98 cerebellum:- brain stem:3.06 corpus callosum/glia:3.41 pineal gland:2.93 peripheral nerve:- spine:3.27 retina:- eye:- artery/aorta:3.72 vein:3.92 lymphnode:4.29 peripheral blood:- spleen:3.99 thymus:4.24 bone marrow:- adipose:3.92 bone:- skin:-
RNA-seq cerebrum:2.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.74 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:29.10 prostate:157.70 ovary:- testis:4.30 heart:38.30 muscle:- esophagus:- stomach:- intestine:- colon:33.90     liver/hepato:-        lung:29.30    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:88.90 breast:9.30 salivary:-
GeneChip uterus:6.77 placenta:6.42 prostate:7.30 ovary:6.93 testis:6.62 heart:6.12 muscle:5.44 esophagus:7.50 stomach:6.79 intestine:6.65 colon:6.92 liver/hepato:6.88 lung:6.72 bladder:- kidney:6.95 pituitary:6.83 thyroid/parathyroid:7.09 adrenal gland:7.01 pancreas:6.89 breast:7.35 salivary:7.18
CAGE uterus:3.54 placenta:3.79 prostate:3.80 ovary:4.05 testis:3.39 heart:3.30 muscle:2.64 esophagus:4.21 stomach:- intestine:3.97 colon:4.18     liver/hepato:4.15    lung:4.06 bladder:3.34 kidney:3.81 pituitary:2.86 thyroid/parathyroid:3.81 adrenal gland:- pancreas:4.16 breast:4.15 salivary:3.90
RNA-seq uterus:- placenta:- prostate:4.55 ovary:4.61 testis:3.92 heart:2.41 muscle:2.79 esophagus:- stomach:- intestine:- colon:3.88     liver/hepato:3.77        lung:3.68    bladder:- kidney:4.33 pituitary:- thyroid/parathyroid:4.09 adrenal gland:4.86 pancreas:- breast:4.36 salivary:-

Gene Information

IDs

Refseq ID NM_012088
Gene ID 25796
Unigene ID Hs.466165
Probe set ID 218388_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130313
GTEx ID ENSG00000130313

Orthologous Gene

Mouse[2]  NM_025396
Rat [0]  

Chromosomal Region

19p13.11  [17,622,432  -  17,632,095]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10518023
11457850
12477932
15489334
16189514
19056867
21044950
21139048
21906983
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0006098  pentose-phosphate shunt
GO:0009051  pentose-phosphate shunt, oxidative branch

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0017057  6-phosphogluconolactonase activity
GO:0048029  monosaccharide binding