forkhead box B1

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Synonym

FKH5, Forkhead box protein B1, forkhead box B1, HFKH-5, FOXB1, Transcription factor FKH-5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:237.30 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.51 cerebellum:3.37 brain stem:3.53 corpus callosum/glia:3.38 pineal gland:- peripheral nerve:3.28 spine:3.28 retina:- eye:- artery/aorta:3.54 vein:3.76 lymphnode:3.44 peripheral blood:- spleen:3.28 thymus:3.25 bone marrow:3.40 adipose:3.65 bone:- skin:3.71
CAGE cerebrum:0.33 cerebellum:- brain stem:1.27 corpus callosum/glia:0.34 pineal gland:0.35 peripheral nerve:- spine:1.86 retina:- eye:- artery/aorta:0 vein:0.18 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:10.60        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.42 placenta:3.10 prostate:3.25 ovary:3.48 testis:3.23 heart:3.59 muscle:3.75 esophagus:3.51 stomach:3.36 intestine:3.54 colon:3.67 liver/hepato:3.35 lung:3.59 bladder:- kidney:3.40 pituitary:3.48 thyroid/parathyroid:3.21 adrenal gland:3.42 pancreas:3.60 breast:3.33 salivary:3.52
CAGE uterus:0.06 placenta:0.24 prostate:0 ovary:0.07 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.09 testis:0.11 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_012182
Gene ID 27023
Unigene ID Hs.160375
Probe set ID 208513_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171956
GTEx ID ENSG00000171956

Orthologous Gene

Mouse[1]  NM_022378
Rat[1]  NM_022378

Chromosomal Region

15q22.2  [60,296,421  -  60,298,142]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

12477932
16344560
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0007412  axon target recognition
GO:0007420  brain development
GO:0009790  embryonic development
GO:0033504  floor plate development
GO:0021855  hypothalamus cell migration
GO:0007595  lactation
GO:0021767  mammilary body development
GO:0030901  midbrain development
GO:0043524  negative regulation of neuron apoptosis
GO:0007389  pattern specification process
GO:0051090  regulation of transcription factor activity
GO:0001756  somitogenesis
GO:0021510  spinal cord development
GO:0022029  telencephalon cell migration
GO:0021794  thalamus development
GO:0009888  tissue development
GO:0001655  urogenital system development
GO:0008542  visual learning

Cellular Component

GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0008134  transcription factor binding