tight junction protein 3 (zona occludens 3)

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Synonym

tight junction protein 3 (zona occludens 3), Zonula occludens 3 protein, ZO3, ZO-3, Tight junction protein ZO-3, TJP3, MGC119546, Zona occludens 3 protein, Tight junction protein 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.16 cerebellum:4.29 brain stem:4.26 corpus callosum/glia:4.04 pineal gland:- peripheral nerve:3.93 spine:3.80 retina:- eye:- artery/aorta:4.52 vein:4.36 lymphnode:4.52 peripheral blood:- spleen:4.03 thymus:4.18 bone marrow:4.03 adipose:4.20 bone:- skin:5.22
CAGE cerebrum:0.07 cerebellum:- brain stem:0.06 corpus callosum/glia:0.52 pineal gland:0.97 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:1.61 vein:0 lymphnode:1.37 peripheral blood:- spleen:0.17 thymus:0.33 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.04 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.79 placenta:4.73 prostate:4.76 ovary:5.24 testis:7.20 heart:3.97 muscle:4.32 esophagus:6.64 stomach:5.78 intestine:5.52 colon:6.29 liver/hepato:5.05 lung:4.88 bladder:- kidney:5.35 pituitary:4.40 thyroid/parathyroid:5.80 adrenal gland:4.12 pancreas:4.73 breast:5.62 salivary:6.74
CAGE uterus:1.03 placenta:1.30 prostate:1.36 ovary:1.25 testis:0.45 heart:0.12 muscle:0.09 esophagus:2.30 stomach:- intestine:3.99 colon:3.66     liver/hepato:2.17    lung:2.47 bladder:1.40 kidney:1.79 pituitary:1.04 thyroid/parathyroid:1.92 adrenal gland:- pancreas:1.98 breast:1.53 salivary:3.38
RNA-seq uterus:- placenta:- prostate:1.38 ovary:1.56 testis:2.67 heart:0.00 muscle:0.17 esophagus:- stomach:- intestine:- colon:1.41     liver/hepato:1.27        lung:1.96    bladder:- kidney:2.04 pituitary:- thyroid/parathyroid:1.74 adrenal gland:0.33 pancreas:- breast:0.71 salivary:-

Gene Information

IDs

Refseq ID NM_014428
Gene ID 27134
Unigene ID -
Probe set ID 35148_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105289
GTEx ID ENSG00000105289

Orthologous Gene

Mouse[1]  NM_013769
Rat[1]  NM_001108073

Chromosomal Region

19p13.3  [3,708,382  -  3,750,810]

Gene Family (Interpro ID)

IPR008144  Guanylate kinase
IPR008145  Guanylate kinase/L-type calcium channel
IPR005417  Zona occludens protein
IPR005420  Zona occludens protein ZO-3

Link to Pubmed  (Pubmed ID)

8889548
9531559
10575001
10601346
11557048
12021270
12477932
14702039
15057824
16344560
17110338
18823282
19807924
21411630

Gene Ontology  (GO ID)

Cellular Component

GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0005923  tight junction

Molecular Function

GO:0005515  protein binding