G protein pathway suppressor 1

 jump to detail

Synonym

GPS1, Signalosome subunit 1, Protein GPS1, Protein MFH, COP9 signalosome complex subunit 1, COPS1, SGN1, CSN1, JAB1-containing signalosome subunit 1, G protein pathway suppressor 1, MGC71287

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:167.10 cerebellum:251.90 brain stem:- corpus callosum/glia:262.50 pineal gland:296.70 peripheral nerve:122.70 spine:- retina:- eye:129.30 artery/aorta:119.90 vein:66.60 lymphnode:111.20 peripheral blood:346.20 spleen:208 thymus:167.50 bone marrow:39.40 adipose:484 bone:166.30 skin:57.60
GeneChip cerebrum:6.70 cerebellum:6.75 brain stem:6.80 corpus callosum/glia:6.57 pineal gland:- peripheral nerve:6.72 spine:6.49 retina:- eye:- artery/aorta:6.41 vein:6.35 lymphnode:6.37 peripheral blood:- spleen:6.20 thymus:6.64 bone marrow:6.14 adipose:6.48 bone:- skin:6.49
CAGE cerebrum:3.64 cerebellum:- brain stem:3.70 corpus callosum/glia:4.02 pineal gland:3.33 peripheral nerve:- spine:3.18 retina:- eye:- artery/aorta:3.23 vein:3.42 lymphnode:3.40 peripheral blood:- spleen:3.41 thymus:3.77 bone marrow:- adipose:3.55 bone:- skin:-
RNA-seq cerebrum:3.57 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.91 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.35 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:116.60 prostate:101.40 ovary:149.10 testis:203.30 heart:191.60 muscle:120.50 esophagus:- stomach:191.20 intestine:356.40 colon:144.20     liver/hepato:63.30        lung:78.20    bladder:1004.90 kidney:156 pituitary:347.90 thyroid/parathyroid:327.50 adrenal gland:457.10 pancreas:35.60 breast:111.50 salivary:656.80
GeneChip uterus:6.47 placenta:6.18 prostate:6.60 ovary:6.43 testis:7.30 heart:6.36 muscle:6.89 esophagus:6.68 stomach:6.20 intestine:6.50 colon:6.37 liver/hepato:6.78 lung:6.55 bladder:- kidney:7.02 pituitary:6.71 thyroid/parathyroid:6.66 adrenal gland:6.34 pancreas:6.65 breast:6.59 salivary:6.83
CAGE uterus:3.48 placenta:3.47 prostate:3.56 ovary:3.74 testis:4.20 heart:3.59 muscle:4.25 esophagus:3.55 stomach:- intestine:3.42 colon:3.27     liver/hepato:3.96    lung:3.25 bladder:3.46 kidney:3.84 pituitary:3.15 thyroid/parathyroid:3.67 adrenal gland:- pancreas:3.93 breast:3.24 salivary:3.69
RNA-seq uterus:- placenta:- prostate:4.37 ovary:4.36 testis:4.77 heart:3.57 muscle:6.14 esophagus:- stomach:- intestine:- colon:3.71     liver/hepato:3.98        lung:3.86    bladder:- kidney:4.20 pituitary:- thyroid/parathyroid:4.42 adrenal gland:4.35 pancreas:- breast:4.19 salivary:-

Gene Information

IDs

Refseq ID NM_004127
Gene ID 2873
Unigene ID Hs.268530
Probe set ID 217782_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169727
GTEx ID ENSG00000169727

Orthologous Gene

Mouse[1]  NM_001177874, NM_145370
Rat[1]  NM_001177874, NM_145370

Chromosomal Region

17q25.3  [80,009,763  -  80,015,346]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
8943324
9535219
9707402
10903862
11114242
11285227
11337588
12220626
12324474
12477932
12615944
12628923
12732143
14702039
15304329
15489334
16036220
16045761
16169070
16260596
16624822
16916636
16949367
16964243
17079684
17276034
17337451
17353931
18606781
18850735
19141280
19295130
19444310
19615732
20360068
20399188
21139048
21145461
21169563
21604193
21890473
21903422
21906983
21963094
22053931
22103747
22190034
22268729
22414063
22505724
22767593
22863883
22939629
23000965
23022380
23275442
23408908
23658844
23818606
23926101
24421388
24654937

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0010388  cullin deneddylation
GO:0000188  inactivation of MAPK activity
GO:0007254  JNK cascade

Cellular Component

GO:0005737  cytoplasm
GO:0008180  signalosome

Molecular Function

GO:0005095  GTPase inhibitor activity