glutamate receptor, ionotropic, delta 2

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Synonym

glutamate receptor, ionotropic, delta 2, MGC117023, MGC117022, MGC117024, GluR-delta-2, Glutamate receptor delta-2 subunit precursor, GLURD2, GRID2, GluR delta-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:30.80 cerebellum:100.80 brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:30.70 spine:- retina:593.20 eye:23.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:38.40 skin:24
GeneChip cerebrum:4 cerebellum:4.20 brain stem:4.10 corpus callosum/glia:3.77 pineal gland:- peripheral nerve:3.78 spine:3.89 retina:- eye:- artery/aorta:3.98 vein:4.15 lymphnode:3.80 peripheral blood:- spleen:3.53 thymus:3.84 bone marrow:4.05 adipose:4.13 bone:- skin:4.11
CAGE cerebrum:2.15 cerebellum:- brain stem:2.13 corpus callosum/glia:1.51 pineal gland:0.55 peripheral nerve:- spine:2.19 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:0 peripheral blood:- spleen:0.09 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:1.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:43.30 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.73 placenta:3.62 prostate:3.70 ovary:3.62 testis:3.76 heart:4.01 muscle:4.28 esophagus:3.86 stomach:3.84 intestine:4.10 colon:4.19 liver/hepato:3.84 lung:3.83 bladder:- kidney:3.92 pituitary:3.93 thyroid/parathyroid:3.60 adrenal gland:3.91 pancreas:4.10 breast:3.78 salivary:3.90
CAGE uterus:0.29 placenta:0 prostate:0.21 ovary:0.92 testis:0.69 heart:0.18 muscle:0.05 esophagus:0 stomach:- intestine:0.07 colon:0.04     liver/hepato:0    lung:0.22 bladder:0.18 kidney:0.08 pituitary:0.26 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.12 testis:1.73 heart:0.10 muscle:0 esophagus:- stomach:- intestine:- colon:0.12     liver/hepato:0        lung:0.21    bladder:- kidney:0.06 pituitary:- thyroid/parathyroid:0.03 adrenal gland:0.00 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001510
Gene ID 2895
Unigene ID Hs.480281
Probe set ID 221364_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000152208
GTEx ID ENSG00000152208

Orthologous Gene

Mouse[4]  NM_008167
Rat [0]  

Chromosomal Region

4q22.1  [93,225,550  -  94,695,707]

Gene Family (Interpro ID)

IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

7506541
9465309
9847074
10234023
10748123
11826110
11829466
12372286
12477932
12573530
12589829
14572453
17027646
18256267
20379614
20487506
20859245
21368048
23251661
23512105
23611888
24078737

Gene Ontology  (GO ID)

Biological Process

GO:0034613  cellular protein localization
GO:0007215  glutamate signaling pathway
GO:0060134  prepulse inhibition
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0043523  regulation of neuron apoptosis
GO:0010975  regulation of neuron projection development
GO:0035249  synaptic transmission, glutamatergic
GO:0006810  transport

Cellular Component

GO:0030054  cell junction
GO:0043197  dendritic spine
GO:0005887  integral to plasma membrane
GO:0008328  ionotropic glutamate receptor complex
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0045202  synapse

Molecular Function

GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0008066  glutamate receptor activity
GO:0004970  ionotropic glutamate receptor activity
GO:0030165  PDZ domain binding