HemK methyltransferase family member 1

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Synonym

MTQ1, HEMK1, HemK methyltransferase family member 1, FLJ22320, HEMK, M.HsaHemKP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.91 cerebellum:5.52 brain stem:6.01 corpus callosum/glia:6.04 pineal gland:- peripheral nerve:6.07 spine:6.09 retina:- eye:- artery/aorta:6.48 vein:5.95 lymphnode:6.58 peripheral blood:- spleen:6.34 thymus:6.73 bone marrow:6.12 adipose:6.10 bone:- skin:6.16
CAGE cerebrum:2.18 cerebellum:- brain stem:2.08 corpus callosum/glia:2.47 pineal gland:2.67 peripheral nerve:- spine:2.53 retina:- eye:- artery/aorta:2.55 vein:1.95 lymphnode:2.35 peripheral blood:- spleen:1.83 thymus:2.48 bone marrow:- adipose:1.86 bone:- skin:-
RNA-seq cerebrum:0.59 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.09 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:22.50 ovary:- testis:4.30 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:17     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.27 placenta:5.80 prostate:6.67 ovary:6.44 testis:7.21 heart:5.94 muscle:6.11 esophagus:6.22 stomach:6.22 intestine:6.33 colon:6.23 liver/hepato:6.32 lung:6.18 bladder:- kidney:6.52 pituitary:6.35 thyroid/parathyroid:6.83 adrenal gland:6.39 pancreas:6.77 breast:6.36 salivary:6.60
CAGE uterus:2.52 placenta:2.29 prostate:2.74 ovary:2.33 testis:2.72 heart:2.20 muscle:1.43 esophagus:2.32 stomach:- intestine:2.13 colon:2.82     liver/hepato:2.08    lung:1.69 bladder:2.09 kidney:2.02 pituitary:2.74 thyroid/parathyroid:2.42 adrenal gland:- pancreas:2.81 breast:2.27 salivary:3.11
RNA-seq uterus:- placenta:- prostate:2.41 ovary:1.93 testis:1.99 heart:0.72 muscle:0.74 esophagus:- stomach:- intestine:- colon:1.23     liver/hepato:1.15        lung:1.26    bladder:- kidney:1.43 pituitary:- thyroid/parathyroid:1.74 adrenal gland:1.56 pancreas:- breast:1.24 salivary:-

Gene Information

IDs

Refseq ID NM_016173
Gene ID 51409
Unigene ID Hs.599362
Probe set ID 52159_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000114735
GTEx ID ENSG00000114735

Orthologous Gene

Mouse[1]  NM_133984
Rat[1]  NM_001106853

Chromosomal Region

3p21.2  [50,606,583  -  50,622,366]

Gene Family (Interpro ID)

IPR004556  Modification methylase HemK
IPR019874  Protein-(glutamine-N5) methyltransferase, release factor-specific

Link to Pubmed  (Pubmed ID)

10690633
12477932
15489334
18541145
20877624

Gene Ontology  (GO ID)

Biological Process

GO:0006306  DNA methylation

Cellular Component

GO:0005739  mitochondrion

Molecular Function

GO:0003677  DNA binding
GO:0008170  N-methyltransferase activity
GO:0008276  protein methyltransferase activity