ATPase, H+ transporting, lysosomal V0 subunit a1

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Synonym

ATP6N1, VPP1, DKFZp781J1951, Vacuolar adenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, ATP6N1A, V-ATPase 116 kDa isoform a1, ATP6V0A1, ATPase, H+ transporting, lysosomal V0 subunit a1, a1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:790.50 cerebellum:1460.90 brain stem:- corpus callosum/glia:320.80 pineal gland:- peripheral nerve:184 spine:1123 retina:355.90 eye:152.80 artery/aorta:30 vein:66.60 lymphnode:70.80 peripheral blood:255.10 spleen:208 thymus:244.80 bone marrow:236.20 adipose:121 bone:217.50 skin:67.20
GeneChip cerebrum:8.92 cerebellum:8.86 brain stem:8.89 corpus callosum/glia:8.33 pineal gland:- peripheral nerve:8.63 spine:8.55 retina:- eye:- artery/aorta:7.72 vein:7.30 lymphnode:7.22 peripheral blood:- spleen:7.64 thymus:7.02 bone marrow:7.62 adipose:7.40 bone:- skin:7.63
CAGE cerebrum:5.41 cerebellum:- brain stem:5.27 corpus callosum/glia:5.40 pineal gland:6.20 peripheral nerve:- spine:5.15 retina:- eye:- artery/aorta:4.11 vein:3.57 lymphnode:3.66 peripheral blood:- spleen:4.10 thymus:3.74 bone marrow:- adipose:4.10 bone:- skin:-
RNA-seq cerebrum:2.97 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.79 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:209.60 placenta:153 prostate:67.60 ovary:37.30 testis:194.70 heart:12.80 muscle:- esophagus:- stomach:- intestine:97.20 colon:135.70     liver/hepato:31.70        lung:78.20    bladder:- kidney:176.80 pituitary:347.90 thyroid/parathyroid:- adrenal gland:50.80 pancreas:80 breast:102.20 salivary:-
GeneChip uterus:7.30 placenta:7.73 prostate:7.59 ovary:7.08 testis:7.83 heart:6.90 muscle:7.58 esophagus:7.57 stomach:7.16 intestine:7.34 colon:7.31 liver/hepato:7.40 lung:7.49 bladder:- kidney:8.04 pituitary:8.75 thyroid/parathyroid:7.81 adrenal gland:7.54 pancreas:7.01 breast:7.62 salivary:6.96
CAGE uterus:4.33 placenta:4.38 prostate:3.85 ovary:3.97 testis:4.30 heart:3.72 muscle:4.57 esophagus:3.80 stomach:- intestine:4.15 colon:3.96     liver/hepato:3.85    lung:4.03 bladder:3.94 kidney:4.76 pituitary:5.21 thyroid/parathyroid:4.10 adrenal gland:- pancreas:3.34 breast:3.19 salivary:4.42
RNA-seq uterus:- placenta:- prostate:0.83 ovary:1.50 testis:2.01 heart:1.89 muscle:3.26 esophagus:- stomach:- intestine:- colon:0.66     liver/hepato:0.60        lung:0.99    bladder:- kidney:2.48 pituitary:- thyroid/parathyroid:2.82 adrenal gland:0.00 pancreas:- breast:0.17 salivary:-

Gene Information

IDs

Refseq ID NM_001130020
Gene ID 535
Unigene ID Hs.463074
Probe set ID 212383_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000033627
GTEx ID ENSG00000033627

Orthologous Gene

Mouse[6]  NM_001243049, NM_001243050, NM_001243051, NM_016920
Rat[6]  NM_001243049, NM_001243050, NM_001243051, NM_016920

Chromosomal Region

17q21.2  [40,610,862  -  40,674,596]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1704894
2874839
7774924
8125298
9210392
9442887
10221984
10224039
10340843
10440860
11836511
12477932
12643545
12649290
12788495
14580332
14597263
15489334
17081065
17360703
17662945
18029348
18187620
18505059
19056867
20038947
21139048
21558123
21674799
21890473
21906983
21963094
21988832
22708544
22939629
23000965
24072707

Gene Ontology  (GO ID)

Biological Process

GO:0015991  ATP hydrolysis coupled proton transport
GO:0006879  cellular iron ion homeostasis
GO:0008286  insulin receptor signaling pathway
GO:0051701  interaction with host
GO:0033572  transferrin transport
GO:0055085  transmembrane transport

Cellular Component

GO:0005737  cytoplasm
GO:0010008  endosome membrane
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0042470  melanosome
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0030670  phagocytic vesicle membrane
GO:0005886  plasma membrane
GO:0000220  vacuolar proton-transporting V-type ATPase, V0 domain

Molecular Function

GO:0051117  ATPase binding
GO:0015078  hydrogen ion transmembrane transporter activity
GO:0005515  protein binding