Ral GEF with PH domain and SH3 binding motif 2

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Synonym

RALGPS2, Ral GEF with PH domain and SH3 binding motif 2, dJ595C2.1, FLJ25604, FLJ10244

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:2.46 cerebellum:- brain stem:2.12 corpus callosum/glia:1.52 pineal gland:4.28 peripheral nerve:- spine:2.46 retina:- eye:- artery/aorta:2.02 vein:4.09 lymphnode:3.98 peripheral blood:- spleen:4.07 thymus:3.42 bone marrow:- adipose:1.84 bone:- skin:-
RNA-seq cerebrum:1.43 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.31 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.08 placenta:2.29 prostate:2.50 ovary:2.89 testis:4.33 heart:2.07 muscle:0.93 esophagus:3.26 stomach:- intestine:3.41 colon:3.30     liver/hepato:3.44    lung:2.51 bladder:2.78 kidney:2.73 pituitary:2.88 thyroid/parathyroid:2.27 adrenal gland:- pancreas:2.26 breast:2.53 salivary:2.31
RNA-seq uterus:- placenta:- prostate:2.10 ovary:2.77 testis:4.23 heart:1.79 muscle:0.61 esophagus:- stomach:- intestine:- colon:2.89     liver/hepato:3.00        lung:1.70    bladder:- kidney:2.21 pituitary:- thyroid/parathyroid:1.88 adrenal gland:3.77 pancreas:- breast:1.18 salivary:-

Gene Information

IDs

Refseq ID NM_152663
Gene ID 55103
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000116191
GTEx ID ENSG00000116191

Orthologous Gene

Mouse[15]  NM_001159965, NM_001159966, NM_001159967, NM_001159968, NM_023884
Rat[1]  NM_001100680, NM_001159966, NM_001159967, NM_001159968, NM_023884

Chromosomal Region

1q25.2  [178,694,300  -  179,065,553]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

10747847
12102558
12477932
12485849
14702039
15324660
15778465
17353931
21139048
21906983
23000965
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0005543  phospholipid binding