exonuclease 3'-5' domain containing 2

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Synonym

exonuclease 3'-5' domain-like 2, FLJ10738, DKFZp781L15100, C14orf114, DKFZp781A0133, Exonuclease 3'-5' domain-like-containing protein 2, chromosome 14 open reading frame 114, EXDL2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.50 cerebellum:6.26 brain stem:6.52 corpus callosum/glia:6.83 pineal gland:- peripheral nerve:6.45 spine:7 retina:- eye:- artery/aorta:6.14 vein:6.25 lymphnode:5.92 peripheral blood:- spleen:5.94 thymus:5.82 bone marrow:5.90 adipose:6.29 bone:- skin:5.96
CAGE cerebrum:3.25 cerebellum:- brain stem:3.20 corpus callosum/glia:3.67 pineal gland:3.30 peripheral nerve:- spine:3.28 retina:- eye:- artery/aorta:2.43 vein:2.39 lymphnode:2.10 peripheral blood:- spleen:2.15 thymus:2.18 bone marrow:- adipose:2.79 bone:- skin:-
RNA-seq cerebrum:0.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.09 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.45 placenta:6.22 prostate:6.66 ovary:6.27 testis:7.45 heart:6.25 muscle:6.39 esophagus:6.33 stomach:6.45 intestine:6.56 colon:6.47 liver/hepato:6 lung:6.32 bladder:- kidney:6.44 pituitary:6.49 thyroid/parathyroid:6.33 adrenal gland:5.95 pancreas:6.69 breast:6.38 salivary:7.03
CAGE uterus:3.02 placenta:1.91 prostate:2.85 ovary:2.65 testis:2.80 heart:2.25 muscle:1.79 esophagus:2.69 stomach:- intestine:2.32 colon:2.54     liver/hepato:2.03    lung:2.44 bladder:2.56 kidney:2.70 pituitary:3.11 thyroid/parathyroid:2.76 adrenal gland:- pancreas:3.65 breast:2.34 salivary:3.56
RNA-seq uterus:- placenta:- prostate:1.41 ovary:0.47 testis:2.15 heart:0.53 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.60     liver/hepato:0.00        lung:1.39    bladder:- kidney:1.82 pituitary:- thyroid/parathyroid:0.00 adrenal gland:1.31 pancreas:- breast:0.51 salivary:-

Gene Information

IDs

Refseq ID NM_018199
Gene ID 55218
Unigene ID Hs.649365
Probe set ID 218363_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000081177
GTEx ID ENSG00000081177

Orthologous Gene

Mouse[1]  NM_133798
Rat [0]  

Chromosomal Region

14q24.1  [69,658,228  -  69,709,075]

Gene Family (Interpro ID)

IPR002562  3'-5' exonuclease
IPR012337  Polynucleotidyl transferase, ribonuclease H fold

Link to Pubmed  (Pubmed ID)

12477932
14702039
15489334
16344560
18029348
21139048
21890473
24654937

Gene Ontology  (GO ID)

Molecular Function

GO:0008408  3'-5' exonuclease activity
GO:0003676  nucleic acid binding