DEP domain containing 1B

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Synonym

DEP domain containing 1B, FLJ11252, XTP1, DEPDC1B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:0.69 cerebellum:- brain stem:1.23 corpus callosum/glia:0.66 pineal gland:0.51 peripheral nerve:- spine:1.76 retina:- eye:- artery/aorta:0.47 vein:1.49 lymphnode:1.25 peripheral blood:- spleen:1.64 thymus:3.41 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.21 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:0.67 placenta:4.66 prostate:0.27 ovary:0.20 testis:3.31 heart:0.24 muscle:0.09 esophagus:1.29 stomach:- intestine:1.77 colon:1.86     liver/hepato:0.14    lung:0.54 bladder:0.26 kidney:0.82 pituitary:0.19 thyroid/parathyroid:0.95 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.04 testis:1.55 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.34     liver/hepato:0.11        lung:0.34    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.59 adrenal gland:0.41 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001145208
Gene ID 55789
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000035499
GTEx ID ENSG00000035499

Orthologous Gene

Mouse[1]  NM_178683
Rat[1]  NM_001107651

Chromosomal Region

5q12.1  [59,892,739  -  59,996,017]

Gene Family (Interpro ID)

IPR000591  DEP domain
IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

12477932
14702039
20923822
21139048
21988832
22990118

Gene Ontology  (GO ID)

Biological Process

GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005096  GTPase activator activity