serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)

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Synonym

dJ461P17.2, Eppin precursor, EPPIN2, EPPIN3, Protease inhibitor WAP7, WAP7, WFDC7, Epididymal protease inhibitor, SPINLW1, WAP four-disulfide core domain protein 7, EPPIN, EPPIN1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:-
GeneChip cerebrum:3.55 cerebellum:3.78 brain stem:3.45 corpus callosum/glia:3.63 pineal gland:- peripheral nerve:3.82 spine:3.63 retina:- eye:- artery/aorta:3.72 vein:3.85 lymphnode:3.51 peripheral blood:- spleen:3.44 thymus:3.43 bone marrow:3.93 adipose:3.73 bone:- skin:3.57
CAGE nodata
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:121.10 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.54 placenta:4.30 prostate:3.35 ovary:3.92 testis:9.42 heart:3.80 muscle:4.03 esophagus:3.47 stomach:3.81 intestine:3.77 colon:4.01 liver/hepato:3.88 lung:3.70 bladder:- kidney:3.77 pituitary:3.62 thyroid/parathyroid:3.63 adrenal gland:3.55 pancreas:4.04 breast:3.49 salivary:3.85
CAGE nodata
RNA-seq uterus:- placenta:- prostate:0.05 ovary:0.47 testis:5.24 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.76    bladder:- kidney:0.10 pituitary:- thyroid/parathyroid:0.03 adrenal gland:0.06 pancreas:- breast:0.04 salivary:-

Gene Information

IDs

Refseq ID NM_020398
Gene ID 57119
Unigene ID Hs.121084
Probe set ID 206319_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000101448
GTEx ID ENSG00000101448

Orthologous Gene

Mouse[1]  NM_029325
Rat[1]  NM_001109457

Chromosomal Region

20q13.12  [44,165,625  -  44,176,391]

Gene Family (Interpro ID)

IPR008197  Whey acidic protein, 4-disulphide core

Link to Pubmed  (Pubmed ID)

11404006
11780052
12206714
12477932
12909348
15229136
15489334
15590901
17207965
17566290
17567961
17644992
17928628
18331357
18466682
18645681
19801569
19889947
20005859
20158997
20488803
20505168
20800364
21392882
21461566
22699487

Gene Ontology  (GO ID)

Biological Process

GO:0042742  defense response to bacterium
GO:0010466  negative regulation of peptidase activity

Cellular Component

GO:0009986  cell surface
GO:0005576  extracellular region

Molecular Function

GO:0005515  protein binding
GO:0004867  serine-type endopeptidase inhibitor activity