RAP1, GTP-GDP dissociation stimulator 1

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Synonym

SMG P21 stimulatory GDP/GTP exchange protein, MGC118859, RAP1GDS1, GDS1, Exchange factor smgGDS, SMG GDS protein, RAP1, GTP-GDP dissociation stimulator 1, MGC118861, Rap1 GTPase-GDP dissociation stimulator 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:86.50 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:61.30 spine:112.30 retina:- eye:47 artery/aorta:89.90 vein:66.60 lymphnode:30.30 peripheral blood:18.20 spleen:75.60 thymus:38.70 bone marrow:39.40 adipose:40.30 bone:38.40 skin:86.40
GeneChip cerebrum:7.79 cerebellum:7.29 brain stem:8.41 corpus callosum/glia:7.60 pineal gland:- peripheral nerve:8.60 spine:7.48 retina:- eye:- artery/aorta:5.67 vein:5.52 lymphnode:6.14 peripheral blood:- spleen:5.96 thymus:7.12 bone marrow:5.72 adipose:5.81 bone:- skin:5.90
CAGE cerebrum:3.91 cerebellum:- brain stem:4.21 corpus callosum/glia:3.90 pineal gland:3.41 peripheral nerve:- spine:3.77 retina:- eye:- artery/aorta:2.59 vein:3.12 lymphnode:3.24 peripheral blood:- spleen:3.09 thymus:3.51 bone marrow:- adipose:2.86 bone:- skin:-
RNA-seq cerebrum:0.38 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:21.90 prostate:22.50 ovary:- testis:30.30 heart:38.30 muscle:- esophagus:- stomach:148.70 intestine:32.40 colon:93.30     liver/hepato:10.60        lung:48.90    bladder:- kidney:93.60 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:55.80 salivary:-
GeneChip uterus:5.78 placenta:4.51 prostate:5.68 ovary:5.39 testis:7.63 heart:4.96 muscle:4.56 esophagus:6.24 stomach:5.28 intestine:5.40 colon:5.28 liver/hepato:5.65 lung:5.84 bladder:- kidney:5.39 pituitary:6.03 thyroid/parathyroid:5.34 adrenal gland:5 pancreas:5.94 breast:5.98 salivary:5.74
CAGE uterus:2.60 placenta:2.19 prostate:2.53 ovary:2.55 testis:2.88 heart:2.60 muscle:1.54 esophagus:2.73 stomach:- intestine:2.80 colon:2.58     liver/hepato:2.68    lung:2.69 bladder:2.84 kidney:2.67 pituitary:3.47 thyroid/parathyroid:2.41 adrenal gland:- pancreas:3.29 breast:2.91 salivary:2.26
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0.34 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.62        lung:0.00    bladder:- kidney:1.26 pituitary:- thyroid/parathyroid:0 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001100430
Gene ID 5910
Unigene ID Hs.132858
Probe set ID 209444_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138698
GTEx ID ENSG00000138698

Orthologous Gene

Mouse[2]  NM_001040690, NM_145544
Rat[1]  NM_001107728, NM_145544

Chromosomal Region

4q23  [99,182,535  -  99,365,012]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1549351
8262526
8900189
11948427
12477932
12690117
14615375
14702039
16189514
17951244
19056867
19260141
19546222
20029029
20190816
20209136
20709748
20936779
21139048
21242305
21429211
21890473
21906983
22505724
22863883
23640485
23898208
24250222
24415755
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0043547  positive regulation of GTPase activity

Cellular Component

GO:0005575  cellular_component

Molecular Function

GO:0005096  GTPase activator activity