BCL2-like 1

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Synonym

bcl-xL, BCLX, DKFZp781P2092, BCL-XL/S, BCL2L1, Bcl-X, Bcl-2-like 1 protein, bcl-xS, BCL2L, BCL2-like 1, Apoptosis regulator Bcl-X

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:237.30 eye:141 artery/aorta:30 vein:- lymphnode:101.10 peripheral blood:- spleen:151.30 thymus:90.20 bone marrow:39.40 adipose:40.30 bone:- skin:120
GeneChip cerebrum:4.65 cerebellum:4.75 brain stem:4.74 corpus callosum/glia:4.74 pineal gland:- peripheral nerve:4.46 spine:4.51 retina:- eye:- artery/aorta:4.49 vein:4.64 lymphnode:4.37 peripheral blood:- spleen:4.31 thymus:6.14 bone marrow:6.17 adipose:4.58 bone:- skin:4.99
CAGE cerebrum:4.47 cerebellum:- brain stem:4.66 corpus callosum/glia:4.67 pineal gland:4.31 peripheral nerve:- spine:4.57 retina:- eye:- artery/aorta:4.78 vein:3.98 lymphnode:3.97 peripheral blood:- spleen:3.90 thymus:4.96 bone marrow:- adipose:4.41 bone:- skin:-
RNA-seq cerebrum:4.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.95 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.45 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:58.30 prostate:67.60 ovary:149.10 testis:51.90 heart:63.90 muscle:- esophagus:- stomach:361.10 intestine:- colon:279.80     liver/hepato:21.10        lung:48.90    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:111.50 salivary:-
GeneChip uterus:4.57 placenta:4.73 prostate:4.95 ovary:4.50 testis:4.66 heart:4.53 muscle:4.41 esophagus:4.94 stomach:4.45 intestine:4.83 colon:4.91 liver/hepato:4.39 lung:4.47 bladder:- kidney:4.92 pituitary:4.21 thyroid/parathyroid:4.18 adrenal gland:4.27 pancreas:5.03 breast:4.28 salivary:4.77
CAGE uterus:3.70 placenta:4.27 prostate:3.88 ovary:3.57 testis:4.41 heart:4.15 muscle:3.77 esophagus:3.95 stomach:- intestine:4.46 colon:3.85     liver/hepato:4.31    lung:4.58 bladder:3.78 kidney:4.66 pituitary:3.83 thyroid/parathyroid:4.22 adrenal gland:- pancreas:3.93 breast:4.81 salivary:3.84
RNA-seq uterus:- placenta:- prostate:4.56 ovary:4.19 testis:4.83 heart:4.48 muscle:4.40 esophagus:- stomach:- intestine:- colon:4.67     liver/hepato:4.50        lung:6.09    bladder:- kidney:5.07 pituitary:- thyroid/parathyroid:5.54 adrenal gland:4.94 pancreas:- breast:4.24 salivary:-

IDs

Refseq ID NM_138578
Gene ID 598
Unigene ID Hs.516966
Probe set ID 206665_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171552
GTEx ID ENSG00000171552

Orthologous Gene

Mouse[3]  NM_009743
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

7540278
7644501
7650367
7834748
8358789
8596636
8692274
8929532
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Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0008637  apoptotic mitochondrial changes
GO:0008283  cell proliferation
GO:0060154  cellular process regulating host cell cycle in response to virus
GO:0071312  cellular response to alkaloid
GO:0071230  cellular response to amino acid stimulus
GO:0071480  cellular response to gamma radiation
GO:0000910  cytokinesis
GO:0009566  fertilization
GO:0007281  germ cell development
GO:0040007  growth
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0008584  male gonad development
GO:0007093  mitotic cell cycle checkpoint
GO:0043066  negative regulation of apoptosis
GO:0010507  negative regulation of autophagy
GO:0090005  negative regulation of establishment of protein localization in plasma membrane
GO:0043524  negative regulation of neuron apoptosis
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0001541  ovarian follicle development
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0046902  regulation of mitochondrial membrane permeability
GO:0051881  regulation of mitochondrial membrane potential
GO:0001836  release of cytochrome c from mitochondria
GO:0046898  response to cycloheximide
GO:0034097  response to cytokine stimulus
GO:0007283  spermatogenesis
GO:0019050  suppression by virus of host apoptosis

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016021  integral to membrane
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion
GO:0031965  nuclear membrane

Molecular Function

GO:0051434  BH3 domain binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0019901  protein kinase binding