tripartite motif-containing 27

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Synonym

Tripartite motif-containing protein 27, RFP, Ret finger protein, RING finger protein 76, RNF76, tripartite motif-containing 27, Zinc finger protein RFP, TRIM27, ret finger protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:445 peripheral nerve:122.70 spine:- retina:- eye:129.30 artery/aorta:30 vein:- lymphnode:111.20 peripheral blood:36.40 spleen:18.90 thymus:12.90 bone marrow:39.40 adipose:80.70 bone:12.80 skin:14.40
GeneChip cerebrum:5.47 cerebellum:5.29 brain stem:5.57 corpus callosum/glia:5.59 pineal gland:- peripheral nerve:5.77 spine:5.60 retina:- eye:- artery/aorta:5.74 vein:5.01 lymphnode:5.85 peripheral blood:- spleen:6.31 thymus:6.55 bone marrow:6.05 adipose:5.95 bone:- skin:5.79
CAGE cerebrum:3.37 cerebellum:- brain stem:3.57 corpus callosum/glia:3.47 pineal gland:3.19 peripheral nerve:- spine:3.28 retina:- eye:- artery/aorta:3.53 vein:3.82 lymphnode:3.85 peripheral blood:- spleen:3.74 thymus:3.81 bone marrow:- adipose:3.27 bone:- skin:-
RNA-seq cerebrum:3.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:69.20 prostate:78.90 ovary:74.50 testis:38.90 heart:76.60 muscle:- esophagus:- stomach:106.20 intestine:- colon:50.90     liver/hepato:31.70        lung:53.80    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:74.30 salivary:-
GeneChip uterus:6.39 placenta:6.05 prostate:6.62 ovary:6.24 testis:6.01 heart:5.56 muscle:5.22 esophagus:5.67 stomach:6.07 intestine:6 colon:6.09 liver/hepato:5.88 lung:5.68 bladder:- kidney:5.69 pituitary:6.51 thyroid/parathyroid:5.77 adrenal gland:5.83 pancreas:6.78 breast:6.01 salivary:6.18
CAGE uterus:3.68 placenta:3.40 prostate:3.52 ovary:3.60 testis:3.39 heart:3.41 muscle:2.48 esophagus:3.08 stomach:- intestine:3.21 colon:3.60     liver/hepato:4.02    lung:3.56 bladder:3.16 kidney:3.31 pituitary:3.89 thyroid/parathyroid:3.65 adrenal gland:- pancreas:4.48 breast:3.30 salivary:3.93
RNA-seq uterus:- placenta:- prostate:4.20 ovary:4.24 testis:3.47 heart:2.43 muscle:2.76 esophagus:- stomach:- intestine:- colon:2.79     liver/hepato:3.89        lung:3.80    bladder:- kidney:4.03 pituitary:- thyroid/parathyroid:3.73 adrenal gland:3.85 pancreas:- breast:3.29 salivary:-

Gene Information

IDs

Refseq ID NM_006510
Gene ID 5987
Unigene ID Hs.440382
Probe set ID 210541_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204713
ENSG00000215641
ENSG00000234495
GTEx ID ENSG00000204713
ENSG00000215641
ENSG00000234495

Orthologous Gene

Mouse[4]  NM_009054
Rat[2]  NM_001106115, NM_001134974

Chromosomal Region

HSCHR6_MHC_APD  [28,870,783  -  28,891,771]
HSCHR6_MHC_MANN  [28,882,558  -  28,891,771]
HSCHR6_MHC_SSTO  [28,870,844  -  28,891,821]
HSCHR6_MHC_MCF  [28,870,945  -  28,891,932]
HSCHR6_MHC_COX  [28,871,599  -  28,892,590]
6p22.1  [28,870,779  -  28,891,766]
HSCHR6_MHC_QBL  [28,870,783  -  28,891,770]

Gene Family (Interpro ID)

IPR001870  B302 (SPRY)-like
IPR003879  Butyrophylin-like
IPR003877  SPla/RYanodine receptor SPRY
IPR018355  SPla/RYanodine receptor subgroup
IPR000315  Zinc finger, B-box
IPR020457  Zinc finger, B-box, chordata

Link to Pubmed  (Pubmed ID)

1437549
2734021
3037315
3078962
3380101
8114113
9247190
9570750
9923704
10504338
10976108
11331580
12445133
12477932
12787916
12807881
14530259
14574404
15489334
15837424
15907835
16007160
16169070
16186106
16189514
16196087
16393995
16475184
16713569
17049487
17156811
18248090
18985028
19060904
19232840
19351825
19549727
19851445
20211142
20526338
20864041
20972456
21078624
21139048
21143188
21145461
21890473
21963094
22053931
22082156
22128329
22493164
22505724
22556269
22829933
23000965
23036196
23105109
23342271
23419514
23452853
23752268
24047820
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0002820  negative regulation of adaptive immune response
GO:0045814  negative regulation of gene expression, epigenetic
GO:0006469  negative regulation of protein kinase activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0032720  negative regulation of tumor necrosis factor production
GO:0070206  protein trimerization
GO:0016567  protein ubiquitination
GO:0007283  spermatogenesis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0031965  nuclear membrane
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0003677  DNA binding
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding
GO:0005515  protein binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding