family with sequence similarity 59, member A

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Synonym

FLJ21610, chromosome 18 open reading frame 11, Gm944, C18orf11, family with sequence similarity 59, member A, FAM59A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:142.20 cerebellum:881.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:92 spine:- retina:118.60 eye:164.60 artery/aorta:119.90 vein:333.20 lymphnode:920 peripheral blood:- spleen:170.20 thymus:193.30 bone marrow:118.10 adipose:524.30 bone:102.40 skin:201.60
GeneChip cerebrum:6.41 cerebellum:6.69 brain stem:6.43 corpus callosum/glia:7.18 pineal gland:- peripheral nerve:6.82 spine:7.17 retina:- eye:- artery/aorta:6.44 vein:5.64 lymphnode:4.49 peripheral blood:- spleen:5.22 thymus:3.81 bone marrow:3.48 adipose:5.52 bone:- skin:6.36
CAGE cerebrum:2.94 cerebellum:- brain stem:3.49 corpus callosum/glia:3.78 pineal gland:1.57 peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:3.03 vein:1.44 lymphnode:1.05 peripheral blood:- spleen:1.21 thymus:0.37 bone marrow:- adipose:3.27 bone:- skin:-
RNA-seq cerebrum:0.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.92 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.81 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:191.40 placenta:83.80 prostate:146.40 ovary:559 testis:121.10 heart:178.80 muscle:100.50 esophagus:1028.50 stomach:212.40 intestine:291.60 colon:195     liver/hepato:105.60        lung:92.90    bladder:251.20 kidney:259.90 pituitary:347.90 thyroid/parathyroid:- adrenal gland:152.40 pancreas:88.90 breast:102.20 salivary:-
GeneChip uterus:5.74 placenta:4.69 prostate:5.97 ovary:5.92 testis:6.18 heart:5.79 muscle:5.40 esophagus:6.49 stomach:6.20 intestine:5.89 colon:5.80 liver/hepato:6.12 lung:4.65 bladder:- kidney:7.07 pituitary:5.41 thyroid/parathyroid:5.17 adrenal gland:6.17 pancreas:7.62 breast:6.37 salivary:6.87
CAGE uterus:2.45 placenta:1.95 prostate:2.40 ovary:2.05 testis:2.72 heart:2.72 muscle:2.33 esophagus:2.62 stomach:- intestine:2.91 colon:2.28     liver/hepato:3.17    lung:2.30 bladder:2.80 kidney:3.07 pituitary:2.32 thyroid/parathyroid:1.71 adrenal gland:- pancreas:3.87 breast:2.27 salivary:3.44
RNA-seq uterus:- placenta:- prostate:0.68 ovary:0.70 testis:2.07 heart:1.57 muscle:1.13 esophagus:- stomach:- intestine:- colon:1.59     liver/hepato:0.68        lung:0.94    bladder:- kidney:1.91 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.44 pancreas:- breast:1.83 salivary:-

Gene Information

IDs

Refseq ID NM_022751
Gene ID 64762
Unigene ID Hs.444314
Probe set ID 219377_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000141441
GTEx ID ENSG00000141441

Orthologous Gene

Mouse[1]  NM_001033445
Rat[1]  NM_001033445

Chromosomal Region

18q12.1  [29,843,506  -  30,050,447]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

12477932
14702039
15489334
15592455
15951569
18854154
19240061
19509291
20379614
20936779
21988832
24003223
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0071364  cellular response to epidermal growth factor stimulus
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade

Cellular Component

GO:0005886  plasma membrane

Molecular Function

GO:0070064  proline-rich region binding
GO:0005515  protein binding