SRY (sex determining region Y)-box 15

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Synonym

SRY (sex determining region Y)-box 20, SOX27, SOX20, SOX-20 protein, SRY (sex determining region Y)-box 15, SOX-15 protein, SOX12, SOX-12 protein, SOX15, SOX26

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:6.44 cerebellum:6.84 brain stem:6.49 corpus callosum/glia:6.33 pineal gland:- peripheral nerve:6.06 spine:6.30 retina:- eye:- artery/aorta:5.94 vein:6.23 lymphnode:6 peripheral blood:- spleen:5.44 thymus:5.59 bone marrow:5.51 adipose:5.94 bone:- skin:7.17
CAGE cerebrum:3.58 cerebellum:- brain stem:3.01 corpus callosum/glia:3.25 pineal gland:3.97 peripheral nerve:- spine:3.27 retina:- eye:- artery/aorta:2.98 vein:1.65 lymphnode:2.13 peripheral blood:- spleen:0.25 thymus:1.36 bone marrow:- adipose:1.44 bone:- skin:-
RNA-seq cerebrum:1.21 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.47 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.28 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:37.30 testis:13 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.30 placenta:5.75 prostate:6.24 ovary:6.38 testis:5.62 heart:6.24 muscle:5.76 esophagus:7.94 stomach:5.95 intestine:6.19 colon:6.10 liver/hepato:5.62 lung:5.95 bladder:- kidney:5.83 pituitary:6.08 thyroid/parathyroid:5.69 adrenal gland:5.66 pancreas:5.74 breast:6.45 salivary:6.05
CAGE uterus:3.43 placenta:0.99 prostate:3.51 ovary:3.43 testis:2.22 heart:2.29 muscle:1.56 esophagus:4.50 stomach:- intestine:1.55 colon:2.54     liver/hepato:0.26    lung:1.42 bladder:3.52 kidney:0.98 pituitary:2.64 thyroid/parathyroid:1.42 adrenal gland:- pancreas:1.21 breast:2.41 salivary:1.58
RNA-seq uterus:- placenta:- prostate:2.83 ovary:2.12 testis:1.41 heart:0.61 muscle:0.14 esophagus:- stomach:- intestine:- colon:1.75     liver/hepato:0.23        lung:1.02    bladder:- kidney:0.33 pituitary:- thyroid/parathyroid:0.67 adrenal gland:0.51 pancreas:- breast:0.35 salivary:-

Gene Information

IDs

Refseq ID NM_006942
Gene ID 6665
Unigene ID Hs.95582
Probe set ID 206122_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000129194
GTEx ID ENSG00000129194

Orthologous Gene

Mouse[1]  NM_009235
Rat [0]  

Chromosomal Region

17p13.1  [7,491,498  -  7,493,488]

Gene Family (Interpro ID)

IPR000910  High mobility group, HMG1/HMG2
IPR009071  High mobility group, superfamily

Link to Pubmed  (Pubmed ID)

8332506
8978787
9540826
9730625
9827568
9880678
10524236
10821863
12100890
12194848
12477932
15367664
15489334
16759287
17363903
18182846
18579725
20211142
22197929
23318427

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0006325  chromatin organization
GO:0008584  male gonad development
GO:0048627  myoblast development
GO:0045843  negative regulation of striated muscle tissue development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0070318  positive regulation of G0 to G1 transition
GO:0014718  positive regulation of satellite cell activation involved in skeletal muscle regeneration
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0043403  skeletal muscle tissue regeneration

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0003700  transcription factor activity