spleen focus forming virus (SFFV) proviral integration oncogene spi1

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Synonym

SFPI1, PU.1, Transcription factor PU.1, SPI1, SPI-A, 31 kDa transforming protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:7.10

cerebellum:12.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:41.10

artery/aorta:-

vein:-

lymphnode:182

peripheral blood:364.40

spleen:151.30

thymus:38.70

bone marrow:216.50

adipose:-

bone:12.80

skin:9.60

GeneChip

cerebrum:4.08

cerebellum:3.92

brain stem:4.20

corpus callosum/glia:4.31

pineal gland:-

peripheral nerve:4.04

spine:4.29

retina:-

eye:-

artery/aorta:4.31

vein:4.37

lymphnode:5.22

peripheral blood:-

spleen:5.61

thymus:3.99

bone marrow:6.75

adipose:4.52

bone:-

skin:4.31

CAGE

cerebrum:2.81

cerebellum:-

brain stem:3.51

corpus callosum/glia:3.64

pineal gland:2.37

peripheral nerve:-

spine:3.66

retina:-

eye:-

artery/aorta:3.19

vein:4.31

lymphnode:4.79

peripheral blood:-

spleen:5.51

thymus:3.57

bone marrow:-

adipose:4.63

bone:-

skin:-

RNA-seq

cerebrum:0.59

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.91

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.26

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:29.10

prostate:11.30

ovary:74.50

testis:4.30

heart:12.80

muscle:-

esophagus:342.80

stomach:42.50

intestine:32.40

colon:17

liver/hepato:21.10

lung:68.40

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:9.30

salivary:-

GeneChip

uterus:3.93

placenta:4.15

prostate:3.61

ovary:4.07

testis:3.75

heart:4.05

muscle:4.14

esophagus:4.11

stomach:3.98

intestine:4.17

colon:4.11

liver/hepato:4.37

lung:6.45

bladder:-

kidney:3.82

pituitary:3.92

thyroid/parathyroid:4.03

adrenal gland:4.12

pancreas:4.02

breast:4.14

salivary:4.02

CAGE

uterus:2.58

placenta:3.72

prostate:3.14

ovary:3.32

testis:2.49

heart:3.47

muscle:2.01

esophagus:3.02

stomach:-

intestine:3.17

colon:2.97

liver/hepato:3.78

lung:5.22

bladder:3.26

kidney:3.23

pituitary:2.21

thyroid/parathyroid:2.79

adrenal gland:-

pancreas:2.54

breast:3.80

salivary:2.50

RNA-seq

uterus:-

placenta:-

prostate:1.20

ovary:0.68

testis:1.53

heart:0.68

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:1.77

lung:0.00

bladder:-

kidney:0.50

pituitary:-

thyroid/parathyroid:0.77

adrenal gland:3.51

pancreas:-

breast:1.91

salivary:-

IDs

Refseq ID	NM_001080547
Gene ID	6688
Unigene ID	Hs.502511
Probe set ID	205312_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000066336
GTEx ID	ENSG00000066336

Orthologous Gene

Mouse[1]	NM_011355
Rat[1]	NM_001005892

Chromosomal Region

11p11.2 [47,376,411 - 47,400,127]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000418	Ets
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0060033	anatomical structure regression
GO:0030218	erythrocyte differentiation
GO:0030851	granulocyte differentiation
GO:0043966	histone H3 acetylation
GO:0044027	hypermethylation of CpG island
GO:0006917	induction of apoptosis
GO:0030098	lymphocyte differentiation
GO:0002320	lymphoid progenitor cell differentiation
GO:0030225	macrophage differentiation
GO:0043011	myeloid dendritic cell differentiation
GO:0045814	negative regulation of gene expression, epigenetic
GO:0045347	negative regulation of MHC class II biosynthetic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0045646	regulation of erythrocyte differentiation
GO:0035019	somatic stem cell maintenance
GO:0001944	vasculature development

Cellular Component

GO:0000790

nuclear chromatin

Molecular Function

GO:0051525	NFAT protein binding
GO:0005515	protein binding
GO:0003723	RNA binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0003700	transcription factor activity

spleen focus forming virus (SFFV) proviral integration oncogene spi1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function