suppressor of Ty 4 homolog 1 (S. cerevisiae)

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Synonym

suppressor of Ty 4 homolog 1 (S. cerevisiae), hSPT4, SPT4H, DRB sensitivity-inducing factor small subunit, SUPT4H, SUPT4H1, DSIF p14, suppressor of Ty (S.cerevisiae) 4 homolog 1, DSIF small subunit, Transcription elongation factor SPT4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.30 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:94 artery/aorta:149.90 vein:66.60 lymphnode:91 peripheral blood:164 spleen:18.90 thymus:38.70 bone marrow:78.70 adipose:282.30 bone:51.20 skin:76.80
GeneChip cerebrum:7.26 cerebellum:7.42 brain stem:7.27 corpus callosum/glia:6.85 pineal gland:- peripheral nerve:7.51 spine:6.96 retina:- eye:- artery/aorta:6.99 vein:7.32 lymphnode:7.10 peripheral blood:- spleen:7.08 thymus:6.90 bone marrow:7.63 adipose:7.10 bone:- skin:7.01
CAGE cerebrum:3.96 cerebellum:- brain stem:3.92 corpus callosum/glia:3.96 pineal gland:3.24 peripheral nerve:- spine:3.65 retina:- eye:- artery/aorta:3.84 vein:4.16 lymphnode:4.10 peripheral blood:- spleen:4.20 thymus:4.17 bone marrow:- adipose:4.10 bone:- skin:-
RNA-seq cerebrum:4.68 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.23 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:83.80 prostate:101.40 ovary:260.80 testis:38.90 heart:127.70 muscle:60.30 esophagus:- stomach:42.50 intestine:97.20 colon:76.30     liver/hepato:42.20        lung:97.80    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:88.90 breast:92.90 salivary:-
GeneChip uterus:7.09 placenta:6.92 prostate:7.30 ovary:7.47 testis:7.47 heart:6.94 muscle:7.79 esophagus:7.20 stomach:6.99 intestine:7 colon:7.07 liver/hepato:6.78 lung:7.17 bladder:- kidney:7.53 pituitary:6.97 thyroid/parathyroid:7.37 adrenal gland:7.35 pancreas:6.86 breast:7.40 salivary:7.17
CAGE uterus:4.20 placenta:4.21 prostate:4.10 ovary:4.09 testis:4.35 heart:3.69 muscle:3.98 esophagus:4.15 stomach:- intestine:4.12 colon:4.04     liver/hepato:4.33    lung:4.00 bladder:4.05 kidney:4.29 pituitary:3.55 thyroid/parathyroid:4.30 adrenal gland:- pancreas:3.99 breast:3.71 salivary:4.23
RNA-seq uterus:- placenta:- prostate:5.27 ovary:4.79 testis:4.94 heart:4.28 muscle:4.05 esophagus:- stomach:- intestine:- colon:4.78     liver/hepato:4.61        lung:4.87    bladder:- kidney:4.81 pituitary:- thyroid/parathyroid:4.85 adrenal gland:5.06 pancreas:- breast:4.50 salivary:-

Gene Information

IDs

Refseq ID NM_003168
Gene ID 6827
Unigene ID Hs.439481
Probe set ID 201484_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000213246
GTEx ID ENSG00000213246

Orthologous Gene

Mouse[2]  NM_009296, NM_011509
Rat[1]  NM_001105828, NM_011509

Chromosomal Region

17q22  [56,422,539  -  56,429,563]

Gene Family (Interpro ID)

IPR009287  Transcription initiation Spt4
IPR016046  Transcription initiation Spt4-like

Link to Pubmed  (Pubmed ID)

7566098
8649394
8786137
9450929
9857195
10075709
10199401
10454543
10757782
10912001
11112772
11553615
12391174
12477932
12612062
12653964
12676794
12718890
14702039
15060154
15136722
15342556
15380072
15489334
16169070
16214896
17502349
17962196
18373978
19210550
19860741
19952111
20211142
21139048
21832049
21890473
21900206
21906983
22422068
22505724
22570620
22939629
23000965
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006338  chromatin remodeling
GO:0010467  gene expression
GO:0032785  negative regulation of RNA elongation
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0032786  positive regulation of RNA elongation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0050434  positive regulation of viral transcription
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0006368  RNA elongation from RNA polymerase II promoter
GO:0006366  transcription from RNA polymerase II promoter
GO:0016032  viral reproduction

Cellular Component

GO:0032044  DSIF complex
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding