proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)

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Synonym

TMG4, PRRG4, Proline-rich Gla protein 4, Proline-rich gamma-carboxyglutamic acid protein 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:25.80 bone marrow:19.70 adipose:- bone:- skin:19.20
GeneChip cerebrum:5.74 cerebellum:6.01 brain stem:5.79 corpus callosum/glia:5.96 pineal gland:- peripheral nerve:7.12 spine:5.79 retina:- eye:- artery/aorta:6 vein:5.72 lymphnode:6.25 peripheral blood:- spleen:6.19 thymus:6.48 bone marrow:6.34 adipose:5.90 bone:- skin:7.11
CAGE cerebrum:0.55 cerebellum:- brain stem:1.23 corpus callosum/glia:1.06 pineal gland:0.35 peripheral nerve:- spine:1.30 retina:- eye:- artery/aorta:1.91 vein:1.44 lymphnode:1.81 peripheral blood:- spleen:1.56 thymus:1.71 bone marrow:- adipose:1.01 bone:- skin:-
RNA-seq cerebrum:0.34 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.80 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.35 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:32.80 prostate:11.30 ovary:- testis:- heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:9.80    bladder:- kidney:31.20 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.13 placenta:6.62 prostate:6.51 ovary:6.36 testis:5.55 heart:5.83 muscle:5.92 esophagus:8.04 stomach:6.11 intestine:6.35 colon:6.24 liver/hepato:7.24 lung:6.86 bladder:- kidney:6.94 pituitary:6.48 thyroid/parathyroid:6.60 adrenal gland:5.94 pancreas:6.44 breast:6.67 salivary:6.84
CAGE uterus:2.01 placenta:3.45 prostate:2.73 ovary:1.46 testis:0.50 heart:0.98 muscle:0.49 esophagus:3.76 stomach:- intestine:3.20 colon:3.00     liver/hepato:2.83    lung:2.88 bladder:2.28 kidney:3.14 pituitary:2.86 thyroid/parathyroid:3.41 adrenal gland:- pancreas:1.59 breast:2.74 salivary:2.53
RNA-seq uterus:- placenta:- prostate:2.70 ovary:1.54 testis:1.46 heart:0.86 muscle:0.69 esophagus:- stomach:- intestine:- colon:2.17     liver/hepato:3.01        lung:3.34    bladder:- kidney:4.02 pituitary:- thyroid/parathyroid:2.79 adrenal gland:1.36 pancreas:- breast:1.36 salivary:-

Gene Information

IDs

Refseq ID NM_024081
Gene ID 79056
Unigene ID Hs.471695
Probe set ID 207291_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135378
GTEx ID ENSG00000135378

Orthologous Gene

Mouse[1]  NM_178695
Rat[1]  NM_001109203

Chromosomal Region

11p13  [32,851,489  -  32,879,669]

Gene Family (Interpro ID)

IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain

Link to Pubmed  (Pubmed ID)

11171957
12477932
15489334
18029348
19772629
21988832
23873930

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process

Cellular Component

GO:0005576  extracellular region
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0003674  molecular_function