pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

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Synonym

HNF1-alpha dimerization cofactor, DcoH-like protein DCoHm, PHS 2, DCOHM, DCOH2, 4-alpha-hydroxy-tetrahydropterin dehydratase 2, PCBD2, Pterin-4-alpha-carbinolamine dehydratase 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:2.19 cerebellum:- brain stem:2.09 corpus callosum/glia:2.47 pineal gland:3.17 peripheral nerve:- spine:2.58 retina:- eye:- artery/aorta:2.17 vein:2.39 lymphnode:2.41 peripheral blood:- spleen:2.21 thymus:2.09 bone marrow:- adipose:2.12 bone:- skin:-
RNA-seq cerebrum:1.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.70 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:2.24 placenta:2.12 prostate:2.22 ovary:1.99 testis:2.16 heart:2.83 muscle:3.84 esophagus:2.56 stomach:- intestine:3.01 colon:2.72     liver/hepato:2.59    lung:2.36 bladder:1.89 kidney:2.66 pituitary:2.57 thyroid/parathyroid:2.31 adrenal gland:- pancreas:2.98 breast:2.19 salivary:3.26
RNA-seq uterus:- placenta:- prostate:2.22 ovary:1.73 testis:1.53 heart:2.85 muscle:2.88 esophagus:- stomach:- intestine:- colon:1.04     liver/hepato:2.09        lung:1.38    bladder:- kidney:2.67 pituitary:- thyroid/parathyroid:2.40 adrenal gland:1.61 pancreas:- breast:2.51 salivary:-

Gene Information

IDs

Refseq ID NM_032151
Gene ID 84105
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000132570
GTEx ID ENSG00000132570

Orthologous Gene

Mouse[1]  NM_028281
Rat[1]  NM_028281

Chromosomal Region

5q31.1  [134,240,596  -  134,343,649]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
11230166
11591653
11980910
12477932
12646162
15182178
15489334
15546961
17353931
18391951
20211142
20877624
21832049
22751105
23263487
23568457

Gene Ontology  (GO ID)

Biological Process

GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051291  protein heterooligomerization
GO:0051289  protein homotetramerization
GO:0006729  tetrahydrobiopterin biosynthetic process

Cellular Component

GO:0005575  cellular_component
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0008124  4-alpha-hydroxytetrahydrobiopterin dehydratase activity
GO:0004505  phenylalanine 4-monooxygenase activity
GO:0005515  protein binding