ADAM metallopeptidase domain 20

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Synonym

ADAM metallopeptidase domain 20, ADAM 20 precursor, ADAM20, a disintegrin and metalloproteinase domain 20, A disintegrin and metalloproteinase domain 20

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:4.42 cerebellum:4.34 brain stem:4.48 corpus callosum/glia:4.18 pineal gland:- peripheral nerve:4.33 spine:4.27 retina:- eye:- artery/aorta:4.34 vein:4.38 lymphnode:4.15 peripheral blood:- spleen:4.10 thymus:4.23 bone marrow:4.67 adipose:4.43 bone:- skin:4.50
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0.14 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.09 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:51.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.12 placenta:4.16 prostate:4.03 ovary:4.02 testis:5.79 heart:4.39 muscle:4.59 esophagus:4.24 stomach:4.21 intestine:4.43 colon:4.47 liver/hepato:4.20 lung:4.09 bladder:- kidney:4.29 pituitary:4.43 thyroid/parathyroid:3.95 adrenal gland:4.32 pancreas:4.44 breast:4.04 salivary:4.21
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:2.10 heart:0 muscle:0.05 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.11 testis:1.67 heart:0.04 muscle:0 esophagus:- stomach:- intestine:- colon:0.05     liver/hepato:0        lung:0    bladder:- kidney:0.09 pituitary:- thyroid/parathyroid:0.03 adrenal gland:0.02 pancreas:- breast:0.11 salivary:-

Gene Information

IDs

Refseq ID NM_003814
Gene ID 8748
Unigene ID Hs.177984
Probe set ID 207423_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134007
GTEx ID ENSG00000134007

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

14q24.2  [70,989,078  -  71,001,732]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9469942
10524237
11807715
12477932
20467438

Gene Ontology  (GO ID)

Biological Process

GO:0007339  binding of sperm to zona pellucida
GO:0032504  multicellular organism reproduction
GO:0006508  proteolysis
GO:0007338  single fertilization

Cellular Component

GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0008270  zinc ion binding