A kinase (PRKA) anchor protein 4

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Synonym

A kinase (PRKA) anchor protein 4, Protein kinase A-anchoring protein 4, AKAP82, AKAP4, FSC1, PRKA4, HI, Major sperm fibrous sheath protein, A-kinase anchor protein 4 precursor, Fsc1, p82, A-kinase anchor protein 82 kDa, AKAP 82, hAKAP82

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.43 cerebellum:4.50 brain stem:4.59 corpus callosum/glia:4.39 pineal gland:- peripheral nerve:4.20 spine:4.25 retina:- eye:- artery/aorta:4.28 vein:4.56 lymphnode:4.29 peripheral blood:- spleen:4.19 thymus:4.13 bone marrow:4.37 adipose:4.36 bone:- skin:4.46
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:246.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.34 placenta:4.26 prostate:4.19 ovary:4.36 testis:9.06 heart:4.50 muscle:4.45 esophagus:4.35 stomach:4.34 intestine:4.43 colon:4.47 liver/hepato:4.40 lung:4.33 bladder:- kidney:4.49 pituitary:4.30 thyroid/parathyroid:4.16 adrenal gland:4.37 pancreas:4.69 breast:4.20 salivary:4.58
CAGE uterus:0 placenta:0.08 prostate:0 ovary:0 testis:5.24 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.00 testis:5.67 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_003886
Gene ID 8852
Unigene ID Hs.97633
Probe set ID 207019_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000147081
GTEx ID ENSG00000147081

Orthologous Gene

Mouse[6]  NM_001042542, NM_009651
Rat[1]  NM_024402, NM_009651

Chromosomal Region

Xp11.22  [49,955,406  -  49,965,664]

Gene Family (Interpro ID)

IPR020799  A-kinase anchor 110kDa
IPR008382  SPHK1-interactor/A-kinase anchor 110kDa

Link to Pubmed  (Pubmed ID)

9238861
9514854
9822690
9852104
11476771
11807172
12477932
12509440
12606363
15489334
15772651
17683036
17712481
21520158
23077236
23451156
23478221
23764900

Gene Ontology  (GO ID)

Biological Process

GO:0030030  cell projection organization
GO:0006928  cellular component movement
GO:0008104  protein localization
GO:0007165  signal transduction
GO:0007338  single fertilization
GO:0030317  sperm motility
GO:0007178  transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0005952  cAMP-dependent protein kinase complex
GO:0005856  cytoskeleton
GO:0031514  motile secondary cilium
GO:0048471  perinuclear region of cytoplasm
GO:0030018  Z disc

Molecular Function

GO:0051018  protein kinase A binding