TRAF-interacting protein with forkhead-associated domain

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Synonym

T2BP, TIFA, MGC20791

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:41.10 artery/aorta:- vein:- lymphnode:121.30 peripheral blood:18.20 spleen:18.90 thymus:25.80 bone marrow:- adipose:- bone:- skin:19.20
GeneChip nodata
CAGE cerebrum:1.62 cerebellum:- brain stem:1.84 corpus callosum/glia:1.21 pineal gland:1.69 peripheral nerve:- spine:1.50 retina:- eye:- artery/aorta:2.74 vein:2.46 lymphnode:3.40 peripheral blood:- spleen:3.26 thymus:2.67 bone marrow:- adipose:1.54 bone:- skin:-
RNA-seq cerebrum:1.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.72 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:29.10 prostate:22.50 ovary:37.30 testis:- heart:12.80 muscle:20.10 esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:-        lung:44    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:- salivary:-
GeneChip nodata
CAGE uterus:2.10 placenta:2.13 prostate:2.27 ovary:2.50 testis:1.32 heart:2.28 muscle:1.40 esophagus:2.76 stomach:- intestine:1.93 colon:2.08     liver/hepato:2.79    lung:2.31 bladder:2.19 kidney:1.80 pituitary:1.58 thyroid/parathyroid:2.89 adrenal gland:- pancreas:3.57 breast:2.19 salivary:3.49
RNA-seq uterus:- placenta:- prostate:2.32 ovary:2.83 testis:2.21 heart:1.90 muscle:1.33 esophagus:- stomach:- intestine:- colon:2.05     liver/hepato:2.39        lung:3.00    bladder:- kidney:2.22 pituitary:- thyroid/parathyroid:2.67 adrenal gland:2.98 pancreas:- breast:1.67 salivary:-

Gene Information

IDs

Refseq ID NM_052864
Gene ID 92610
Unigene ID Hs.310640
Probe set ID -
Ensembl ID ENSG00000145365
GTEx ID ENSG00000145365

Orthologous Gene

Mouse[1]  NM_145133
Rat[1]  NM_001014044

Chromosomal Region

4q25  [113,196,783  -  113,207,059]

Gene Family (Interpro ID)

IPR000253  Forkhead-associated
IPR008984  SMAD/FHA domain

Link to Pubmed  (Pubmed ID)

1179819
8889548
11798190
12477932
12566447
12761501
15047173
15492226
16189514
16643855
19322201
20332099
21139048
21890473
21906983
21963094
22505724
22566686

Gene Ontology  (GO ID)

Biological Process

GO:0007249  I-kappaB kinase/NF-kappaB cascade

Molecular Function

GO:0005515  protein binding