kelch-like 21 (Drosophila)

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Synonym

kelch-like 21 (Drosophila), Kelch-like protein 21, KLHL21, KIAA0469, MGC99635

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:131.60 cerebellum:352.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:52.90 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:54.70 spleen:- thymus:77.30 bone marrow:39.40 adipose:- bone:64 skin:33.60
GeneChip cerebrum:6.49 cerebellum:6.33 brain stem:6.58 corpus callosum/glia:7.08 pineal gland:- peripheral nerve:6.67 spine:6.60 retina:- eye:- artery/aorta:7.18 vein:7.02 lymphnode:6.22 peripheral blood:- spleen:6.24 thymus:6.05 bone marrow:6.05 adipose:6.67 bone:- skin:6.99
CAGE cerebrum:2.35 cerebellum:- brain stem:3.24 corpus callosum/glia:3.54 pineal gland:1.29 peripheral nerve:- spine:2.82 retina:- eye:- artery/aorta:3.65 vein:2.74 lymphnode:2.60 peripheral blood:- spleen:1.95 thymus:1.86 bone marrow:- adipose:2.87 bone:- skin:-
RNA-seq cerebrum:2.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.50 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:47.40 prostate:180.20 ovary:37.30 testis:155.80 heart:76.60 muscle:60.30 esophagus:- stomach:63.70 intestine:32.40 colon:42.40     liver/hepato:52.80        lung:117.30    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:- breast:65.10 salivary:-
GeneChip uterus:6.66 placenta:5.42 prostate:6.83 ovary:6.66 testis:6.29 heart:7.10 muscle:7.84 esophagus:7.06 stomach:6.34 intestine:6.38 colon:6.06 liver/hepato:6.32 lung:6.21 bladder:- kidney:7.17 pituitary:6.72 thyroid/parathyroid:6.58 adrenal gland:7.01 pancreas:6.43 breast:7.32 salivary:7.29
CAGE uterus:2.77 placenta:1.96 prostate:3.42 ovary:2.80 testis:2.44 heart:2.94 muscle:3.97 esophagus:3.21 stomach:- intestine:1.88 colon:2.73     liver/hepato:2.66    lung:2.75 bladder:3.57 kidney:2.32 pituitary:2.32 thyroid/parathyroid:2.88 adrenal gland:- pancreas:3.40 breast:3.80 salivary:2.66
RNA-seq uterus:- placenta:- prostate:4.90 ovary:2.77 testis:3.07 heart:3.68 muscle:5.88 esophagus:- stomach:- intestine:- colon:3.62     liver/hepato:2.46        lung:3.19    bladder:- kidney:2.97 pituitary:- thyroid/parathyroid:4.46 adrenal gland:2.57 pancreas:- breast:3.76 salivary:-

Gene Information

IDs

Refseq ID NM_014851
Gene ID 9903
Unigene ID Hs.7764
Probe set ID 203068_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000162413
GTEx ID ENSG00000162413

Orthologous Gene

Mouse[1]  NM_001033352
Rat[1]  NM_001107996

Chromosomal Region

1p36.31  [6,650,784  -  6,674,667]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like

Link to Pubmed  (Pubmed ID)

9455484
12477932
14702039
16303743
16710414
19995937
21145461
21906983
21963094
21987572
22053931
22505724
23455478
23676014
24778252

Gene Ontology  (GO ID)

Biological Process

GO:0051322  anaphase
GO:0000910  cytokinesis
GO:0007067  mitosis
GO:0016567  protein ubiquitination

Cellular Component

GO:0031463  Cul3-RING ubiquitin ligase complex
GO:0005737  cytoplasm
GO:0005827  polar microtubule

Molecular Function

GO:0004842  ubiquitin-protein ligase activity