Rho GTPase activating protein 25

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Synonym

Rho-GTPase-activating protein 25, KIAA0053, ARHGAP25, Rho GTPase activating protein 25

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.70 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:- artery/aorta:- vein:- lymphnode:151.70 peripheral blood:200.40 spleen:321.40 thymus:167.50 bone marrow:137.80 adipose:- bone:12.80 skin:48
GeneChip cerebrum:5.37 cerebellum:5.14 brain stem:5.46 corpus callosum/glia:5.55 pineal gland:- peripheral nerve:5.29 spine:5.65 retina:- eye:- artery/aorta:5.59 vein:5.68 lymphnode:7.72 peripheral blood:- spleen:8.29 thymus:6.60 bone marrow:7.58 adipose:6.46 bone:- skin:5.72
CAGE cerebrum:1.66 cerebellum:- brain stem:2.45 corpus callosum/glia:2.67 pineal gland:1.29 peripheral nerve:- spine:2.73 retina:- eye:- artery/aorta:2.08 vein:4.17 lymphnode:4.38 peripheral blood:- spleen:4.50 thymus:3.60 bone marrow:- adipose:2.84 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.92 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:21.90 prostate:11.30 ovary:149.10 testis:- heart:- muscle:20.10 esophagus:- stomach:- intestine:32.40 colon:195     liver/hepato:-        lung:39.10    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:46.50 salivary:-
GeneChip uterus:5.65 placenta:5.55 prostate:5.28 ovary:6 testis:5.11 heart:5.79 muscle:5.61 esophagus:5.57 stomach:5.96 intestine:5.88 colon:6.04 liver/hepato:5.91 lung:6.78 bladder:- kidney:5.52 pituitary:5.37 thyroid/parathyroid:5.45 adrenal gland:5.71 pancreas:5.75 breast:5.98 salivary:5.66
CAGE uterus:2.12 placenta:2.01 prostate:2.19 ovary:2.50 testis:1.72 heart:2.04 muscle:1.40 esophagus:1.93 stomach:- intestine:2.45 colon:1.91     liver/hepato:2.25    lung:3.58 bladder:2.26 kidney:1.79 pituitary:1.29 thyroid/parathyroid:1.35 adrenal gland:- pancreas:1.74 breast:2.27 salivary:2.12
RNA-seq uterus:- placenta:- prostate:0.75 ovary:1.57 testis:0.23 heart:0.88 muscle:0.01 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.89        lung:2.80    bladder:- kidney:1.52 pituitary:- thyroid/parathyroid:0.00 adrenal gland:3.97 pancreas:- breast:0.94 salivary:-

Gene Information

IDs

Refseq ID NM_001166276
Gene ID 9938
Unigene ID Hs.531807
Probe set ID 38149_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163219
GTEx ID ENSG00000163219

Orthologous Gene

Mouse[2]  NM_001037727, NM_175476
Rat[1]  NM_001109247, NM_175476

Chromosomal Region

2p13.3  [68,906,733  -  69,053,965]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology
IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

7584044
12477932
15254788
15489334
19911011
21890473
24159190

Gene Ontology  (GO ID)

Biological Process

GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005096  GTPase activator activity
GO:0005543  phospholipid binding