glutamate receptor, metabotropic 7

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Synonym

Grm7, C030018L03, Gpr1g, 6330570A01Rik, glutamate receptor, metabotropic 7, BB176677, Metabotropic glutamate receptor 7 precursor, MGC90857, Mglur7, Gprc1g, mGluR7, E130018M02Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:3.22 cerebellum:- brain stem:3.72 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.65 retina:- eye:- artery/aorta:0.25 vein:- lymphnode:0.23 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0.63 skin:0.15
RNA-seq cerebrum:3.96 cerebellum:3.96 brain stem:3.96 corpus callosum/glia:3.96 pineal gland:3.96 peripheral nerve:3.96 spine:3.96 retina:3.96 eye:3.96 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:2.03 placenta:0.11 prostate:1.02 ovary:2.54 testis:0 heart:- muscle:- esophagus:- stomach:1.07 intestine:0.58 colon:0.57     liver/hepato:0    lung:0 bladder:0.57 kidney:- pituitary:1.22 thyroid/parathyroid:- adrenal gland:1.26 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_177328
Gene ID 108073
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000056755

Orthologous Gene

Human[8]  NM_000844, NM_181874
Rat [0]  

Chromosomal Region

6E3  [110,595,575  -  111,517,224]

Gene Family (Interpro ID)

IPR000337  GPCR, family 3
IPR000162  GPCR, family 3, metabotropic glutamate receptor
IPR001786  GPCR, family 3, metabotropic glutamate receptor 4
IPR001883  GPCR, family 3, metabotropic glutamate receptor 7

Link to Pubmed  (Pubmed ID)

9069281
9920659
10349636
10550060
11042159
11076861
11217851
11584003
11698585
11706005
12065412
12466851
12477932
12679517
12814372
15313036
15489334
16024054
16141072
16141073
16204199
16237391
16602821
16775145
17114649
17156446
17273929
17311335
17553999
17650109
17936574
18287559
18289889
18534761
18641645
18716219
18799693
19047183
20353761
20423346
21143597
21396450
21677750
22287544
22564442
22723691
23174341
23382219
23603202
23664812
24596089

Gene Ontology  (GO ID)

Biological Process

GO:0030534  adult behavior
GO:0008306  associative learning
GO:0001662  behavioral fear response
GO:0070588  calcium ion transmembrane transport
GO:0001661  conditioned taste aversion
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007196  inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway
GO:0007613  memory
GO:0033555  multicellular organismal response to stress
GO:0007194  negative regulation of adenylate cyclase activity
GO:0030818  negative regulation of cAMP biosynthetic process
GO:0014050  negative regulation of glutamate secretion
GO:0050877  neurological system process
GO:0050896  response to stimulus
GO:0007608  sensory perception of smell
GO:0007605  sensory perception of sound
GO:0007614  short-term memory
GO:0007165  signal transduction
GO:0007268  synaptic transmission
GO:0019226  transmission of nerve impulse

Cellular Component

GO:0032279  asymmetric synapse
GO:0030424  axon
GO:0005938  cell cortex
GO:0043025  cell soma
GO:0009986  cell surface
GO:0030425  dendrite
GO:0043198  dendritic shaft
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0043679  nerve terminal
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0048786  presynaptic active zone
GO:0048787  presynaptic active zone membrane
GO:0042734  presynaptic membrane
GO:0043234  protein complex
GO:0005791  rough endoplasmic reticulum
GO:0045202  synapse
GO:0043195  terminal button

Molecular Function

GO:0001640  adenylate cyclase inhibiting metabotropic glutamate receptor activity
GO:0010855  adenylate cyclase inhibitor activity
GO:0005246  calcium channel regulator activity
GO:0005509  calcium ion binding
GO:0048306  calcium-dependent protein binding
GO:0005516  calmodulin binding
GO:0004930  G-protein coupled receptor activity
GO:0016595  glutamate binding
GO:0008066  glutamate receptor activity
GO:0001642  group III metabotropic glutamate receptor activity
GO:0030165  PDZ domain binding
GO:0042803  protein homodimerization activity
GO:0070905  serine binding
GO:0004871  signal transducer activity
GO:0005245  voltage-gated calcium channel activity