adrenergic receptor, alpha 2a

Synonym

Alpha-2A adrenoceptor, Alpha-2A adrenergic receptor, adrenergic receptor, alpha 2a, alpha2-C10, Alpha-2A adrenoreceptor, AW122659, alpha2A-adrenergic receptor, Adra-2, Alpha-2AAR, alpha2A, subtype alpha2-C10, Adra-2a, Adra2a

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:26

cerebellum:36.80

brain stem:603.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:141.90

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:638.20

bone:-

skin:15.80

GeneChip

cerebrum:5.25

cerebellum:5.34

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.06

spine:6.45

retina:4.78

eye:4.85

artery/aorta:-

vein:4.74

lymphnode:5.08

peripheral blood:-

spleen:4.52

thymus:-

bone marrow:4.95

adipose:4.82

bone:4.83

skin:4.65

CAGE

cerebrum:2.24

cerebellum:-

brain stem:3.51

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.85

retina:-

eye:-

artery/aorta:1.78

vein:-

lymphnode:2.23

peripheral blood:-

spleen:0.41

thymus:0.67

bone marrow:-

adipose:-

bone:1.30

skin:1.67

RNA-seq

cerebrum:3.12

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:65.50

intestine:37

colon:158.60

liver/hepato:-

lung:-

bladder:66.20

kidney:8.10

pituitary:25.80

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:5.41

placenta:4.69

prostate:5.01

ovary:4.74

testis:4.43

heart:4.88

muscle:4.90

esophagus:-

stomach:6.78

intestine:6.02

colon:-

liver/hepato:5.06

lung:4.71

bladder:4.64

kidney:4.87

pituitary:4.61

thyroid/parathyroid:-

adrenal gland:4.35

pancreas:5.46

breast:4.61

salivary:4.82

CAGE

uterus:2.26

placenta:0.57

prostate:1.69

ovary:1.38

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.75

intestine:2.60

colon:2.30

liver/hepato:0

lung:0.91

bladder:1.86

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:0.56

pancreas:1.30

breast:1.50

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.24

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007417
Gene ID	11551
Unigene ID	Mm.235195
Probe set ID	1423022_at [Mouse430_2]
Ensembl ID	ENSMUSG00000033717

Orthologous Gene

Human[1]	NM_000681
Rat[1]	NM_000681

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR001946	Adrenergic receptor, alpha-2A
IPR015695	Adrenergic receptor, alpha-2A/2B/2C
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0032870	cellular response to hormone stimulus
GO:0042596	fear response
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042593	glucose homeostasis
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0046676	negative regulation of insulin secretion
GO:0050995	negative regulation of lipid catabolic process
GO:0030335	positive regulation of cell migration
GO:0001819	positive regulation of cytokine production
GO:0045741	positive regulation of epidermal growth factor receptor activity
GO:0043406	positive regulation of MAP kinase activity
GO:0051044	positive regulation of membrane protein ectodomain proteolysis
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0004935	adrenoceptor activity
GO:0031696	alpha-2C adrenergic receptor binding
GO:0004938	alpha2-adrenergic receptor activity
GO:0051379	epinephrine binding
GO:0004930	G-protein coupled receptor activity
GO:0032795	heterotrimeric G-protein binding
GO:0051380	norepinephrine binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0004871	signal transducer activity
GO:0031996	thioesterase binding

adrenergic receptor, alpha 2a

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function