adrenergic receptor, beta 2

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Synonym

Adrb2, Beta-2 adrenergic receptor, adrenergic receptor, beta 2, beta 2-adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Adrb2r, Badm, Gpcr7, beta 2-AR, Adrb-2

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.72 cerebellum:3.83 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.90 spine:3.65 retina:3.71 eye:5.02 artery/aorta:- vein:5.98 lymphnode:6.56 peripheral blood:- spleen:6.63 thymus:- bone marrow:7.45 adipose:4.58 bone:7.32 skin:6.42
CAGE cerebrum:1.92 cerebellum:- brain stem:1.77 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.96 retina:- eye:- artery/aorta:4.18 vein:- lymphnode:3.87 peripheral blood:- spleen:4.30 thymus:3.07 bone marrow:- adipose:- bone:4.59 skin:3.40
RNA-seq cerebrum:0.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:288.20 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.49 placenta:3.82 prostate:4.64 ovary:4.66 testis:3.98 heart:3.93 muscle:7.16 esophagus:- stomach:3.73 intestine:3.83 colon:- liver/hepato:4.05 lung:8.28 bladder:4.27 kidney:4.49 pituitary:3.83 thyroid/parathyroid:- adrenal gland:4.06 pancreas:4.34 breast:5.06 salivary:4.23
CAGE uterus:3.48 placenta:1.95 prostate:3.50 ovary:2.78 testis:0.75 heart:- muscle:- esophagus:- stomach:2.26 intestine:0.58 colon:1.85     liver/hepato:2.26    lung:5.12 bladder:2.73 kidney:- pituitary:2.77 thyroid/parathyroid:- adrenal gland:2.09 pancreas:3.36 breast:3.48 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0.57        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_007420
Gene ID 11555
Unigene ID Mm.55982
Probe set ID 1437302_at  [Mouse430_2]
Ensembl ID ENSMUSG00000045730

Orthologous Gene

Human[1]  NM_000024
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1354640
1628813
1676978
1686018
2154750
2549959
2569767
2834198
3141418
6321299
7651355
7738011
7873877
7949735
8094989
8099512
8160017
8288218
8308019
8396717
8597598
8693001
8770105
9139936
9235896
9305915
9506519
9826121
10066919
10349636
10358008
10358009
10878340
10922068
11042159
11076861
11214319
11217851
11448841
11502890
11557593
11641423
11679434
11737201
11748583
11782469
12055247
12097322
12161655
12205107
12297500
12352327
12387862
12466851
12477932
12509508
12615050
12734361
12925702
12933684
12954981
14500986
14625387
14966518
14990578
15016730
15066901
15336560
15474034
15585594
15724149
15791602
15802488
15939797
16001069
16002745
16040722
16113068
16141072
16141073
16171811
16458323
16602821
16645459
16670773
16767221
16790355
16876797
16920928
16996249
17115048
17170700
17296797
17404268
17435077
17442405
17446185
17498818
17510209
17515456
17543594
17873881
17885689
17996646
18006484
18056263
18188154
18193078
18194271
18245567
18256599
18305025
18421015
18436820
18511502
18694395
18761104
18801900
18814142
18820136
18851973
19047375
19059194
19084064
19095863
19103808
19167076
19171883
19213958
19333138
19364979
19420258
19596833
19633206
19706446
19706594
19801680
19837877
19855129
19865483
19926878
20059989
20138019
20185685
20197056
20335229
20363288
20395378
20395454
20406048
20413718
20443853
20613718
20705779
20805681
20836991
20864554
21130738
21131397
21138422
21148315
21177286
21209093
21224388
21266510
21267068
21282381
21335487
21366703
21368050
21389089
21419339
21444660
21680711
21705675
21833475
21857681
21878527
21976502
21990347
22028912
22227600
22315324
22323706
22407956
22442147
22457517
22495178
22500016
22538810
22593095
22683571
22863835
22912718
22913394
23090606
23093370
23129275
23133676
23219791
23243208
23287463
23312282
23382219
23418295
23420884
23430246
23436577
23473322
23644514
23684624
23745588
23894672
23920331
23984976
24011077
24058627
24121404
24140643
24170934
24562381

Gene Ontology  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0045453  bone resorption
GO:0050873  brown fat cell differentiation
GO:0002032  desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002086  diaphragm contraction
GO:0002024  diet induced thermogenesis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0031649  heat generation
GO:0016525  negative regulation of angiogenesis
GO:0050728  negative regulation of inflammatory response
GO:0040015  negative regulation of multicellular organism growth
GO:0030279  negative regulation of ossification
GO:0045986  negative regulation of smooth muscle contraction
GO:0043065  positive regulation of apoptosis
GO:0030501  positive regulation of bone mineralization
GO:0008284  positive regulation of cell proliferation
GO:0045823  positive regulation of heart contraction
GO:0043410  positive regulation of MAPKKK cascade
GO:0043268  positive regulation of potassium ion transport
GO:0031398  positive regulation of protein ubiquitination
GO:0048633  positive regulation of skeletal muscle tissue growth
GO:0010765  positive regulation of sodium ion transport
GO:0003059  positive regulation of the force of heart contraction by epinephrine
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045909  positive regulation of vasodilation
GO:0006898  receptor-mediated endocytosis
GO:0051924  regulation of calcium ion transport
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0051930  regulation of sensory perception of pain
GO:0006940  regulation of smooth muscle contraction
GO:0002028  regulation of sodium ion transport
GO:0001993  regulation of systemic arterial blood pressure by norepinephrine-epinephrine
GO:0042312  regulation of vasodilation
GO:0009409  response to cold
GO:0007165  signal transduction
GO:0035249  synaptic transmission, glutamatergic
GO:0002025  vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060  wound healing

Cellular Component

GO:0016324  apical plasma membrane
GO:0030424  axon
GO:0005901  caveola
GO:0032809  cell soma membrane
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0044424  intracellular part
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043235  receptor complex
GO:0042383  sarcolemma

Molecular Function

GO:0008179  adenylate cyclase binding
GO:0004935  adrenoceptor activity
GO:0004941  beta2-adrenergic receptor activity
GO:0035240  dopamine binding
GO:0008144  drug binding
GO:0051379  epinephrine binding
GO:0001965  G-protein alpha-subunit binding
GO:0004930  G-protein coupled receptor activity
GO:0035255  ionotropic glutamate receptor binding
GO:0051380  norepinephrine binding
GO:0015459  potassium channel regulator activity
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity
GO:0004871  signal transducer activity