ATPase, H+ transporting, lysosomal V1 subunit B2

 jump to detail

Synonym

Atp6v1b2, Endomembrane proton pump 58 kDa subunit, AI194269, Vacuolar proton pump B isoform 2, Vacuolar ATP synthase subunit B, brain isoform, lysosomal 56/58kDa, R74844, V-ATPase B2 subunit, HO57, Atp6b2, Vat2, ATPase, H+ transporting, lysosomal V1 subunit B2, AI790362

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:36.80 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:10.41 cerebellum:9.90 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.35 spine:10.34 retina:7.83 eye:6.34 artery/aorta:- vein:7.93 lymphnode:8.07 peripheral blood:- spleen:7.60 thymus:- bone marrow:8.49 adipose:8.21 bone:8.43 skin:6.64
CAGE cerebrum:5.09 cerebellum:- brain stem:5.50 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.47 retina:- eye:- artery/aorta:3.77 vein:- lymphnode:3.74 peripheral blood:- spleen:3.35 thymus:3.23 bone marrow:- adipose:- bone:3.94 skin:3.46
RNA-seq cerebrum:94.27 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:10    bladder:- kidney:8.10 pituitary:12.90 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:8.15 placenta:8.97 prostate:7.81 ovary:7.59 testis:6.45 heart:7.62 muscle:8.03 esophagus:- stomach:7.61 intestine:7.69 colon:- liver/hepato:7.25 lung:8.03 bladder:7.41 kidney:9.85 pituitary:9.14 thyroid/parathyroid:- adrenal gland:8.11 pancreas:7.13 breast:7.78 salivary:5.19
CAGE uterus:3.70 placenta:3.92 prostate:4.04 ovary:3.47 testis:3.77 heart:- muscle:- esophagus:- stomach:3.54 intestine:3.65 colon:3.55     liver/hepato:3.08    lung:3.79 bladder:3.33 kidney:- pituitary:4.54 thyroid/parathyroid:- adrenal gland:4.13 pancreas:2.83 breast:3.41 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:7.15 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.45        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007509
Gene ID 11966
Unigene ID Mm.392573
Probe set ID 1419883_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000006273

Orthologous Gene

Human[1]  NM_001693
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7945239
8741845
8772466
8889548
10349636
10922068
11042159
11076861
11217851
12466851
12477932
14681479
14720510
15013950
15226823
15489334
15782199
16141072
16141073
16177003
17114649
17392376
17898041
17971301
18614564
18667600
18719589
18799693
18945877
19723774
20711468
20837476
21267068
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0015991  ATP hydrolysis coupled proton transport
GO:0046034  ATP metabolic process
GO:0006811  ion transport
GO:0015992  proton transport
GO:0006810  transport

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005902  microvillus
GO:0005886  plasma membrane
GO:0033178  proton-transporting two-sector ATPase complex, catalytic domain
GO:0033180  proton-transporting V-type ATPase, V1 domain

Molecular Function

GO:0005524  ATP binding
GO:0016787  hydrolase activity
GO:0016820  hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances