B-cell leukemia/lymphoma 6

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Synonym

B-cell leukemia/lymphoma 6, Bcl5, Bcl-6, B-cell lymphoma 6 protein homolog, Bcl6

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:39.90

cerebellum:147.40

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:94.60

retina:32.10

eye:22.80

artery/aorta:168.80

vein:-

lymphnode:43.20

peripheral blood:-

spleen:105.30

thymus:415

bone marrow:230.80

adipose:425.40

bone:50.10

skin:110.80

GeneChip

cerebrum:7.36

cerebellum:9.21

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:7.75

spine:7.38

retina:8.02

eye:8.73

artery/aorta:-

vein:7.11

lymphnode:8.43

peripheral blood:-

spleen:8.87

thymus:-

bone marrow:7.63

adipose:7.95

bone:7.98

skin:9.54

CAGE

cerebrum:4.39

cerebellum:-

brain stem:3.22

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.60

retina:-

eye:-

artery/aorta:4.77

vein:-

lymphnode:4.92

peripheral blood:-

spleen:3.37

thymus:4.79

bone marrow:-

adipose:-

bone:3.10

skin:3.93

RNA-seq

cerebrum:8.95

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:87.20

placenta:13.80

prostate:-

ovary:-

testis:7.40

heart:18.60

muscle:35.50

esophagus:-

stomach:-

intestine:-

colon:17.60

liver/hepato:18.10

lung:130.50

bladder:66.20

kidney:8.10

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:45.70

salivary:-

GeneChip

uterus:7.45

placenta:6.88

prostate:8.24

ovary:7.25

testis:5.05

heart:7.75

muscle:10.06

esophagus:-

stomach:6.60

intestine:6.83

colon:-

liver/hepato:9.11

lung:8.08

bladder:7.78

kidney:8.63

pituitary:6.10

thyroid/parathyroid:-

adrenal gland:7.54

pancreas:7.14

breast:7.61

salivary:8.69

CAGE

uterus:3.48

placenta:2.79

prostate:2.84

ovary:3.21

testis:1.18

heart:-

muscle:-

esophagus:-

stomach:2.44

intestine:2.76

colon:2.92

liver/hepato:2.78

lung:3.89

bladder:3.54

kidney:-

pituitary:2.39

thyroid/parathyroid:-

adrenal gland:3.59

pancreas:3.27

breast:2.51

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:7.32

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:8.78

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_009744
Gene ID	12053
Unigene ID	Mm.347398
Probe set ID	1421818_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022508

Orthologous Gene

Human[5]	NM_001130845, NM_001134738, NM_001706
Rat[1]	NM_001107084, NM_001134738, NM_001706

Chromosomal Region

Gene Family (Interpro ID)

IPR011333	BTB/POZ fold
IPR000210	BTB/POZ-like
IPR015880	Zinc finger, C2H2-like

Gene Ontology (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0030183	B cell differentiation
GO:0000902	cell morphogenesis
GO:0048821	erythrocyte development
GO:0002467	germinal center formation
GO:0043066	negative regulation of apoptosis
GO:0045596	negative regulation of cell differentiation
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0001953	negative regulation of cell-matrix adhesion
GO:0048294	negative regulation of isotype switching to IgE isotypes
GO:0032764	negative regulation of mast cell cytokine production
GO:0035024	negative regulation of Rho protein signal transduction
GO:0045629	negative regulation of T-helper 2 cell differentiation
GO:0002829	negative regulation of T-helper 2 type immune response
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0043065	positive regulation of apoptosis
GO:0030890	positive regulation of B cell proliferation
GO:0051272	positive regulation of cellular component movement
GO:0000060	protein import into nucleus, translocation
GO:0008104	protein localization
GO:0042127	regulation of cell proliferation
GO:0050727	regulation of inflammatory response
GO:0043380	regulation of memory T cell differentiation
GO:0032319	regulation of Rho GTPase activity
GO:0006355	regulation of transcription, DNA-dependent
GO:0006974	response to DNA damage stimulus
GO:0007266	Rho protein signal transduction
GO:0007283	spermatogenesis
GO:0042092	T-helper 2 type immune response
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005634	nucleus
GO:0005657	replication fork

Molecular Function

GO:0003682	chromatin binding
GO:0031490	chromatin DNA binding
GO:0003677	DNA binding
GO:0046872	metal ion binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

B-cell leukemia/lymphoma 6

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function